{"id":"W1971680848","doi":"10.1182/blood-2008-04-152934","title":"Heme oxygenase-1 expression enhances vascular endothelial resistance to complement-mediated injury through induction of decay-accelerating factor: a role for increased bilirubin and ferritin","year":2008,"lang":"en","type":"article","venue":"Blood","topic":"Heme Oxygenase-1 and Carbon Monoxide","field":"Biochemistry, Genetics and Molecular Biology","cited_by":81,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Versus Arthritis; McGill University","keywords":"HMOX1; Heme oxygenase; Decay-accelerating factor; Hemin; Biliverdin; Heme; Chemistry; Molecular biology; Ferritin; Cytoprotection; Endothelial stem cell; Complement system; Cell biology; Biology; Biochemistry; Oxidative stress; Immunology; Antibody; In vitro; Enzyme","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001835525,0.0002311264,0.0002236333,0.000175333,0.0001150768,0.0003072822,0.0002189234,0.0002658734,0.001145057],"category_scores_gemma":[0.0001223188,0.00009868345,0.0001981668,0.0001142317,0.000183941,0.00016991,0.000111639,0.0004844913,0.0001946143],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003297649,"about_ca_system_score_gemma":0.0001866376,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005741894,"about_ca_topic_score_gemma":0.0005118213,"domain_scores_codex":[0.9998895,0.0000213298,0.00001073809,0.00002208617,0.00002335518,0.0000330225],"domain_scores_gemma":[0.9998909,0.0000147788,0.00003027397,0.00001173854,0.00001748266,0.00003474902],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001334582,0.00002946509,0.00009012654,0.0000279607,0.000002537138,0.00002878772,0.00001019955,0.00002075486,0.9985934,0.00008787562,0.00002221985,0.000953276],"study_design_scores_gemma":[0.00002754921,0.0003085229,0.004350669,0.000006410661,0.00001929466,0.0001741312,0.00001678315,0.000827164,0.9929241,0.00005982158,0.001281558,0.000003964206],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9954525,0.001556597,0.001798512,0.0001654542,0.00002457014,0.00001989242,0.0001080406,0.00007188542,0.0008026265],"genre_scores_gemma":[0.9951787,0.0008486271,0.001511848,0.00005670356,0.00001300785,0.00002367899,0.0001453494,0.000008994783,0.002213048],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001145057,"threshold_uncertainty_score":0.003830612,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02114328769802483,"score_gpt":0.2569876083803682,"score_spread":0.2358443206823434,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}