{"id":"W1971727510","doi":"10.1017/s0031182005007559","title":"<i>Toxoplasma gondii</i>dense granule protein 3 (GRA3) is a type I transmembrane protein that possesses a cytoplasmic dilysine (KKXX) endoplasmic reticulum (ER) retrieval motif","year":2005,"lang":"en","type":"article","venue":"Parasitology","topic":"Toxoplasma gondii Research Studies","field":"Immunology and Microbiology","cited_by":34,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"National Institute of Allergy and Infectious Diseases","keywords":"Endoplasmic reticulum; Biology; Signal peptide; Transmembrane protein; ER retention; Toxoplasma gondii; Transmembrane domain; Peptide sequence; Cytoplasm; Protein targeting; Cell biology; Fusion protein; Secretory protein; Secretory pathway; Membrane protein; Molecular biology; Antibody; Recombinant DNA; Biochemistry; Secretion; Amino acid; Receptor; Genetics; Gene; Golgi apparatus; Membrane","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.000666446,0.001009556,0.001560629,0.0006024511,0.0007880084,0.0000908505,0.001015911,0.001136616,0.002013683],"category_scores_gemma":[0.0006899718,0.0009131724,0.0004127994,0.001008071,0.001611926,0.0003819975,0.000305039,0.001712472,0.006249987],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002008348,"about_ca_system_score_gemma":0.000413928,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001751266,"about_ca_topic_score_gemma":0.0005374737,"domain_scores_codex":[0.9937643,0.001071017,0.001024933,0.001581656,0.000328813,0.002229278],"domain_scores_gemma":[0.9972556,0.000530318,0.0004262236,0.001181225,0.000409262,0.0001973709],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00362136,0.0007558264,0.005051035,0.0002506219,0.0008865678,0.0003198552,0.001481642,0.00002568259,0.9793784,0.0006793232,0.006518317,0.00103134],"study_design_scores_gemma":[0.004669845,0.001166406,0.002634994,0.0001377772,0.0001849092,0.00176495,0.0003015909,0.00004903764,0.8902921,0.0003088312,0.09759555,0.0008940284],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9807236,0.004775129,0.0001903355,0.008179507,0.0008337703,0.002684541,0.0002538289,0.0005178722,0.001841401],"genre_scores_gemma":[0.9822531,0.0004657096,0.000875347,0.000417508,0.0002002558,0.0003624396,0.0002993349,0.0001308315,0.01499544],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.09107724,"threshold_uncertainty_score":0.9993319,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01832936737391054,"score_gpt":0.2835889331904888,"score_spread":0.2652595658165782,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}