{"id":"W1971744331","doi":"10.1038/mt.2010.171","title":"Blocking the Myostatin Signal With a Dominant Negative Receptor Improves the Success of Human Myoblast Transplantation in Dystrophic Mice","year":2010,"lang":"en","type":"article","venue":"Molecular Therapy","topic":"Muscle Physiology and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":42,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"Canadian Institutes of Health Research; National Institutes of Health","keywords":"Myostatin; Duchenne muscular dystrophy; Dystrophin; Transplantation; Biology; Myocyte; Muscular dystrophy; Utrophin; Regeneration (biology); Cell biology; Skeletal muscle; Cancer research; Molecular biology; Internal medicine; Endocrinology; Medicine; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001762618,0.0001359963,0.0001144309,0.00002597585,0.0001188285,0.00001275282,0.000253032,0.00008886571,0.00001900336],"category_scores_gemma":[0.000009581951,0.00007501533,0.00005699815,0.0001033735,0.0002924585,0.000004173061,0.00001544698,0.0001947744,7.529234e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000002504693,"about_ca_system_score_gemma":0.00004285277,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001812554,"about_ca_topic_score_gemma":0.0005015975,"domain_scores_codex":[0.9992086,0.0001524263,0.0001597243,0.000215671,0.0000970343,0.0001666022],"domain_scores_gemma":[0.9995472,0.00003454461,0.0001122032,0.0002319674,0.00005426826,0.00001977201],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008164075,0.00006285958,0.0004836749,0.000009316182,0.00005115198,0.000002433875,0.0007993256,0.0001030868,0.9959267,0.0002087997,0.000007572358,0.001528679],"study_design_scores_gemma":[0.001350132,0.0006011312,0.01066485,0.00001374371,0.00001082705,0.000004617809,0.0002964112,0.00003537392,0.9864789,0.0002973073,0.0001313,0.0001153574],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9982951,0.0001770687,0.0007046689,0.0003336648,0.00003467616,0.0003377658,0.00000905403,0.000003272982,0.0001047865],"genre_scores_gemma":[0.9993271,0.00009447047,0.0001314086,0.0002798949,0.00003440519,0.00006254976,0.00003877799,0.00001660793,0.00001478723],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01018117,"threshold_uncertainty_score":0.3059037,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004120824167347354,"score_gpt":0.2306064308641135,"score_spread":0.2264856066967662,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}