{"id":"W1971819575","doi":"10.1074/jbc.m109671200","title":"Protein Kinase C-δ (PKC-δ) Is Activated by Type I Interferons and Mediates Phosphorylation of Stat1 on Serine 727","year":2002,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Cytokine Signaling Pathways and Interactions","field":"Medicine","cited_by":219,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; University Health Network","funders":"National Cancer Institute","keywords":"Phosphorylation; Protein kinase C; Serine; Kinase; Cell biology; Protein kinase A; Chemistry; STAT1; Cancer research; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001173284,0.0007648355,0.0002573642,0.0004501036,0.0003429241,0.0004155898,0.0002234385,0.0002944528,0.002657191],"category_scores_gemma":[0.0001183511,0.0001696971,0.0002926061,0.0004389003,0.000250628,0.0002310434,0.0003389386,0.0006582312,0.001933853],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005861801,"about_ca_system_score_gemma":0.0005203297,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008920863,"about_ca_topic_score_gemma":0.0007644347,"domain_scores_codex":[0.9998399,0.00001277354,0.00001217368,0.00003540909,0.00004538253,0.00005430076],"domain_scores_gemma":[0.999896,0.000005852524,0.00004402843,0.000009439133,0.00001961913,0.0000250281],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001038069,0.0001582044,0.00285983,0.0006647633,0.00004141396,0.0004853766,0.00003511273,0.0004054098,0.9510812,0.001281477,0.001208982,0.04074019],"study_design_scores_gemma":[0.0001817838,0.0004106691,0.04256844,0.00009597107,0.00006421453,0.002450529,0.00009027831,0.001863291,0.9072853,0.0009344108,0.04402625,0.00002879799],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8975546,0.06547145,0.01341582,0.001233059,0.0006677871,0.0002191997,0.00175538,0.000545884,0.01913688],"genre_scores_gemma":[0.9645138,0.01911572,0.002875323,0.0001869395,0.00008591055,0.00008512208,0.001471884,0.00002184211,0.01164348],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002657191,"threshold_uncertainty_score":0.008889258,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03590822237731316,"score_gpt":0.2709271730117681,"score_spread":0.2350189506344549,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}