{"id":"W1971837501","doi":"10.1089/10430340252792503","title":"Adenovirus Vector-Induced Inflammation: Capsid-Dependent Induction of the C-C Chemokine RANTES Requires NF- <i>κ</i> B","year":2002,"lang":"en","type":"article","venue":"Human Gene Therapy","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":86,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"Canadian Institutes of Health Research; Alberta Heritage Foundation for Medical Research","keywords":"Chemokine; Transduction (biophysics); Molecular biology; Adenoviridae; Biology; Inflammation; Cell biology; Signal transduction; HeLa; Genetic enhancement; Cell; Immunology; Gene; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003423239,0.000240922,0.0002146646,0.00007745707,0.0002426159,0.00003234176,0.0005555916,0.0001888473,0.0005283134],"category_scores_gemma":[0.0000229275,0.0001877808,0.0001674782,0.000211363,0.0001556084,0.00001092889,0.0001026121,0.0001921633,0.00002397929],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003825911,"about_ca_system_score_gemma":0.00005024018,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004160086,"about_ca_topic_score_gemma":0.0001327106,"domain_scores_codex":[0.9982418,0.000217692,0.0003782517,0.0003900978,0.0004481057,0.0003240908],"domain_scores_gemma":[0.9986317,0.0000115867,0.0002071015,0.0009143408,0.0001674546,0.0000678773],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004629126,0.00009471472,0.000199311,0.000009760074,0.0001140551,0.000001791848,0.0002546419,0.00006363896,0.98894,0.00002674521,0.0006966904,0.009135711],"study_design_scores_gemma":[0.001711625,0.001588624,0.001147722,0.0000123952,0.000009177307,0.00001475325,0.000036714,0.00001884677,0.9927533,0.00009657838,0.002400825,0.0002094012],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9951936,0.002876241,0.00001224297,0.0006377656,0.0001873347,0.0004610326,0.00001123238,0.00002591393,0.0005946437],"genre_scores_gemma":[0.9964784,0.001251687,0.00002343197,0.0002193434,0.0008246576,0.00005607375,0.00003075773,0.00005302921,0.001062601],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00892631,"threshold_uncertainty_score":0.7657478,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04820848814826027,"score_gpt":0.2910092560336451,"score_spread":0.2428007678853848,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}