{"id":"W1971866921","doi":"10.4161/cc.20095","title":"PHF19 and Akt control the switch between proliferative and invasive states in melanoma","year":2012,"lang":"en","type":"article","venue":"Cell Cycle","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":44,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Nautical Research Society","funders":"","keywords":"Biology; Homeobox protein NANOG; Protein kinase B; Chromatin immunoprecipitation; Gene silencing; Cell biology; Cancer research; Gene expression; Molecular biology; Promoter; Signal transduction; Embryonic stem cell; Genetics; Gene; Induced pluripotent stem cell","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000073332,0.0002276592,0.0001373515,0.0002211052,0.0001429444,0.0002699672,0.0001069987,0.0002043469,0.001222343],"category_scores_gemma":[0.00007397,0.0001418466,0.0001907843,0.00009122898,0.0001603243,0.0001593535,0.0001754459,0.0003229897,0.0002785789],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003216664,"about_ca_system_score_gemma":0.0001193375,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004980984,"about_ca_topic_score_gemma":0.0008433854,"domain_scores_codex":[0.9999257,0.000007813655,0.000006445543,0.00001952439,0.00001500919,0.00002545205],"domain_scores_gemma":[0.999929,0.000009680459,0.00002286984,0.000006263481,0.00000637588,0.00002586424],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001240469,0.00001966984,0.0005426521,0.00001439127,0.000003185424,0.00004486069,0.00000878485,0.00004293614,0.9981773,0.0000856764,0.00002472675,0.000911788],"study_design_scores_gemma":[0.00003274638,0.0001776934,0.04003408,0.000003979917,0.00001549722,0.0002243386,0.0000597313,0.001987496,0.9547313,0.0001431746,0.002582781,0.00000715112],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9959929,0.001094657,0.00134031,0.00005847628,0.0000207097,0.00001828383,0.0003116218,0.00005566463,0.001107372],"genre_scores_gemma":[0.9970894,0.0004333085,0.0005983579,0.00002948821,0.000004983008,0.00001486486,0.0002102793,0.00001190961,0.001607375],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001222343,"threshold_uncertainty_score":0.004089117,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00718286239426137,"score_gpt":0.2292791498538496,"score_spread":0.2220962874595882,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}