{"id":"W1971875923","doi":"10.1139/y02-029","title":"Discovery of recently adopted orphan receptors for apelin, urotensin II, and ghrelin identified using novel radioligands and functional role in the human cardiovascular system","year":2002,"lang":"en","type":"review","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Cardiovascular, Neuropeptides, and Oxidative Stress Research","field":"Medicine","cited_by":61,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"British Heart Foundation","keywords":"Urotensin-II; Apelin; Ghrelin; Receptor; Orphan receptor; Vasodilation; Internal medicine; Endocrinology; G protein-coupled receptor; Biology; Adrenomedullin; Medicine; Pharmacology; Biochemistry; Gene","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00110358,0.0003018359,0.002094321,0.0006184845,0.0002680739,0.00002023404,0.0001411618,0.0002955983,0.00003992788],"category_scores_gemma":[0.00009567197,0.0002148659,0.0006635361,0.0002516995,0.0005712227,0.00009204377,0.00004477055,0.0007686131,2.719793e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001227972,"about_ca_system_score_gemma":0.0006205884,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004445421,"about_ca_topic_score_gemma":0.0001330134,"domain_scores_codex":[0.9976431,0.0007009287,0.0007383151,0.0003652824,0.0001788676,0.0003735301],"domain_scores_gemma":[0.9985665,0.0003165656,0.0003626871,0.0001908874,0.0002980047,0.0002653179],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.002597968,0.0007265028,0.001166587,0.1272292,0.05190133,0.002495562,0.003481814,0.0005692668,0.3357697,0.0008372939,0.01297973,0.4602451],"study_design_scores_gemma":[0.01173924,0.001597456,0.00272278,0.008580268,0.01550745,0.01333742,0.0007414485,0.0002311126,0.001722064,0.00005848119,0.9429868,0.0007754331],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.1037266,0.8946542,0.00004654058,0.00003297141,0.0005745777,0.0008318129,0.0001040952,0.000002079602,0.00002712502],"genre_scores_gemma":[0.1430028,0.8557662,0.00005022293,0.00008847477,0.0009207682,0.00002306819,0.0000627363,0.00003789553,0.00004778586],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9300071,"threshold_uncertainty_score":0.8761976,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08332632631859553,"score_gpt":0.3295375675051031,"score_spread":0.2462112411865076,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}