{"id":"W1971907398","doi":"10.1021/bi060522c","title":"Biochemical Consequences of Heritable Mutations in the α-Tocopherol Transfer Protein","year":2006,"lang":"en","type":"article","venue":"Biochemistry","topic":"Antioxidant Activity and Oxidative Stress","field":"Medicine","cited_by":50,"is_retracted":false,"has_abstract":true,"ca_institutions":"Brock University","funders":"National Institute of Diabetes and Digestive and Kidney Diseases","keywords":"Endocytic cycle; Vitamin E deficiency; Secretion; Mutation; Biology; Tocopherol; Vitamin; Intracellular; Cell biology; Vitamin E; Transport protein; Chemistry; Gene; Genetics; Biochemistry; Endocytosis; Cell; Antioxidant","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001415886,0.0007399924,0.0002508132,0.0004725919,0.0001908982,0.0002186038,0.0002294203,0.0005769864,0.001389781],"category_scores_gemma":[0.000444773,0.0001938742,0.0003208668,0.0002259782,0.0005795528,0.0001620024,0.0004319423,0.0004906668,0.0002249483],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000232879,"about_ca_system_score_gemma":0.0001721607,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006448476,"about_ca_topic_score_gemma":0.0005091405,"domain_scores_codex":[0.9997843,0.0000465055,0.00004294805,0.00005572698,0.00004683834,0.00002378426],"domain_scores_gemma":[0.999648,0.00008668409,0.0001415141,0.00003428685,0.00002295095,0.00006649279],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001669959,0.00003407698,0.001333842,0.00002896981,0.00002584437,0.001494974,0.00001942055,0.0001637479,0.9951345,0.0001259332,0.00003174628,0.001439841],"study_design_scores_gemma":[0.00007038645,0.0009914709,0.065679,0.00001479125,0.0001435146,0.01795606,0.0001164073,0.001997707,0.910786,0.0003064477,0.001907617,0.00003058348],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9968155,0.0007229244,0.001458008,0.00005398781,0.00002177281,0.00001408222,0.0003625388,0.00009550218,0.0004557701],"genre_scores_gemma":[0.9984891,0.0004179256,0.0005115728,0.00001393522,0.000005724319,0.000008690917,0.0001730007,0.0000212248,0.0003586965],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001389781,"threshold_uncertainty_score":0.004649222,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01394184111336844,"score_gpt":0.2580260155987498,"score_spread":0.2440841744853814,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}