{"id":"W1971925153","doi":"10.1038/labinvest.2010.207","title":"Vhl is required for normal pancreatic β cell function and the maintenance of β cell mass with age in mice","year":2011,"lang":"en","type":"article","venue":"Laboratory Investigation","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":22,"is_retracted":false,"has_abstract":false,"ca_institutions":"St. Michael's Hospital; Ontario Institute for Cancer Research; University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"GLUT2; Endocrinology; Internal medicine; Biology; Islet; Angiogenesis; Conditional gene knockout; Transcription factor; Knockout mouse; Pancreatic islets; Glucose transporter; Insulin; Cancer research; Medicine; Phenotype; Gene; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003331579,0.0001097189,0.0002326791,0.00006942605,0.0000410006,0.000007729995,0.00003515667,0.00006765994,0.00002534681],"category_scores_gemma":[0.000098669,0.0000713751,0.00002317346,0.0002864835,0.0003017072,0.0001397212,0.000006292036,0.00008067057,0.00000460163],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002660653,"about_ca_system_score_gemma":0.0001112801,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005734422,"about_ca_topic_score_gemma":0.00001367468,"domain_scores_codex":[0.9992575,0.00006802539,0.0002448753,0.000167314,0.000123197,0.0001390702],"domain_scores_gemma":[0.9993095,0.0001122875,0.000171013,0.0001649745,0.0001688826,0.00007329243],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003897709,0.0001226519,0.2240816,0.00114013,0.0000575076,0.000005986907,0.005825262,0.000006627493,0.758491,0.004626669,0.001654851,0.0000899727],"study_design_scores_gemma":[0.01705201,0.001124241,0.1808348,0.0003917294,0.0005054573,0.000002448222,0.002353641,0.001400122,0.789639,0.005773006,0.0006788862,0.0002447053],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9943082,0.0002070939,0.0007387198,0.0002181752,0.0000678829,0.0005863585,0.00001642599,0.00002299323,0.003834116],"genre_scores_gemma":[0.9927304,0.00002361561,0.004926708,0.001563826,0.000035511,0.00009703653,0.00002331041,0.0000144354,0.0005851129],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04324682,"threshold_uncertainty_score":0.2910592,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01687925753187282,"score_gpt":0.1999110738279864,"score_spread":0.1830318162961135,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}