{"id":"W1971930005","doi":"10.1021/ac202599b","title":"Polymerase Chain Reaction-Free, Sample-to-Answer Bacterial Detection in 30 Minutes with Integrated Cell Lysis","year":2011,"lang":"en","type":"article","venue":"Analytical Chemistry","topic":"Biosensors and Analytical Detection","field":"Engineering","cited_by":63,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Lysis; Chemistry; Detection limit; Polymerase chain reaction; Bacteria; Microbiological culture; Real-time polymerase chain reaction; Sample preparation; Bacterial cell structure; Chromatography; Computational biology; Microbiology; Nanotechnology; Biology; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002817773,0.002332229,0.001458611,0.0006838656,0.0003092637,0.0009942183,0.001395914,0.001449323,0.001758076],"category_scores_gemma":[0.002726768,0.001297134,0.0007661453,0.0006729523,0.001136105,0.0008466896,0.001036218,0.001959701,0.002277086],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005154646,"about_ca_system_score_gemma":0.0008978478,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003341101,"about_ca_topic_score_gemma":0.0009760956,"domain_scores_codex":[0.9939732,0.001328175,0.0005246436,0.001582749,0.002182068,0.0004090324],"domain_scores_gemma":[0.9986411,0.0005148555,0.0002817445,0.0002798982,0.0002007361,0.00008168536],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001500952,0.0001254969,0.0002686483,0.0002085754,0.00002874792,0.00006849305,0.00008994754,0.0002442227,0.9891554,0.0003067501,0.0003635792,0.008990082],"study_design_scores_gemma":[0.00004605247,0.0004775394,0.0006379403,0.00001972353,0.00004065659,0.0002658749,0.000016837,0.006048901,0.9868034,0.0001756942,0.005437826,0.00002959224],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"empirical","genre_scores_codex":[0.1187418,0.002895189,0.8713124,0.000309929,0.0004555673,0.001004617,0.0002837611,0.00333915,0.001657681],"genre_scores_gemma":[0.2072482,0.001989546,0.7782503,0.0004797919,0.0001115985,0.002754667,0.001184349,0.000271027,0.007710564],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.002817773,"threshold_uncertainty_score":0.014902,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008828108230617424,"score_gpt":0.1792603610994289,"score_spread":0.1704322528688115,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}