{"id":"W1971930005","doi":"10.1021/ac202599b","title":"Polymerase Chain Reaction-Free, Sample-to-Answer Bacterial Detection in 30 Minutes with Integrated Cell Lysis","year":2011,"lang":"en","type":"article","venue":"Analytical Chemistry","topic":"Biosensors and Analytical Detection","field":"Engineering","cited_by":63,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Lysis; Chemistry; Detection limit; Polymerase chain reaction; Bacteria; Microbiological culture; Real-time polymerase chain reaction; Sample preparation; Bacterial cell structure; Chromatography; Computational biology; Microbiology; Nanotechnology; Biology; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007393727,0.000230537,0.000250508,0.00009785148,0.00003447809,0.00003234386,0.0001409808,0.000210363,0.0008871649],"category_scores_gemma":[0.00009965924,0.0002009033,0.00008548193,0.0005787408,0.00004998402,0.00008239134,0.00002559927,0.0003195623,0.00004097438],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001236268,"about_ca_system_score_gemma":0.00002590522,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006582686,"about_ca_topic_score_gemma":0.0001940509,"domain_scores_codex":[0.9989246,0.00001319879,0.0002820657,0.0003071091,0.000157935,0.0003151204],"domain_scores_gemma":[0.9993148,0.00004960064,0.00002614779,0.0003229909,0.00005403265,0.0002323931],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003055048,0.0002891051,0.0007003256,0.0001574103,0.0001184203,0.00004021914,0.0001018166,0.0001201113,0.988651,0.00002986052,0.000542799,0.008943364],"study_design_scores_gemma":[0.0005340751,0.00007171439,0.00130019,0.00004794909,0.00009864011,0.00001104109,0.0001425595,0.02627163,0.9692631,0.0001246239,0.001734765,0.0003997409],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9822696,0.00002472038,0.004034886,0.00005343085,0.0001086669,0.00008889676,0.00003066749,0.000207773,0.01318133],"genre_scores_gemma":[0.9985151,0.00000805641,0.0005727723,0.00005894915,0.0001682413,0.0000162272,0.00002158807,0.00003465042,0.0006044052],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02615152,"threshold_uncertainty_score":0.9713833,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008828108230617424,"score_gpt":0.1792603610994289,"score_spread":0.1704322528688115,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}