{"id":"W1971955922","doi":"10.1159/000218894","title":"Molecular Pathogenesis of Adenocarcinomas in Barrett’s Esophagus: Role of the Tumor Suppressor Gene p53","year":2009,"lang":"en","type":"article","venue":"Onkologie","topic":"Esophageal Cancer Research and Treatment","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Mount Sinai Hospital","funders":"","keywords":"Esophagus; Pathogenesis; Tumor suppressor gene; Barrett's esophagus; Adenocarcinoma; Cancer research; Suppressor; Biology; Pathology; Esophageal disease; Cancer; Esophageal cancer; Mutation; Epithelium; Gene; Medicine; Carcinogenesis; Internal medicine; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006404116,0.0003886238,0.0003994775,0.001393466,0.0002451144,0.0005436339,0.0002523253,0.0006432027,0.0009807644],"category_scores_gemma":[0.0005940259,0.0001915454,0.0002312878,0.0004003436,0.0005095252,0.0006523323,0.0002917606,0.0004216915,0.00024029],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003251837,"about_ca_system_score_gemma":0.0002444877,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004346831,"about_ca_topic_score_gemma":0.0003368039,"domain_scores_codex":[0.9998462,0.00006899007,0.00001330159,0.00001331424,0.0000346512,0.00002340857],"domain_scores_gemma":[0.9997926,0.00005077783,0.00006094973,0.00001928913,0.00003647752,0.00003999977],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.006660198,0.0008148239,0.3623729,0.002002829,0.0004408836,0.0230225,0.0005065855,0.002049538,0.3599517,0.01133376,0.003226252,0.227618],"study_design_scores_gemma":[0.000310732,0.00218256,0.817058,0.0004211162,0.0006473394,0.08735444,0.0008840204,0.003628779,0.0592075,0.007948357,0.02029584,0.00006133123],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7823977,0.2084305,0.002269002,0.00265109,0.0001055696,0.00004490541,0.00008231029,0.00005552941,0.003963487],"genre_scores_gemma":[0.9521957,0.04552064,0.000930503,0.0001345526,0.0001669755,0.0000136525,0.00007256104,0.000004975482,0.0009604305],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001393466,"threshold_uncertainty_score":0.003386855,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01861891200638116,"score_gpt":0.2854541933771773,"score_spread":0.2668352813707961,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}