{"id":"W1971964490","doi":"10.1016/j.exphem.2010.05.009","title":"Induction of pluripotency in human cord blood unrestricted somatic stem cells","year":2010,"lang":"en","type":"article","venue":"Experimental Hematology","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":54,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Deutsche Forschungsgemeinschaft; Max-Planck-Gesellschaft; Stem Cell Network; Bundesministerium für Bildung und Forschung; Natural Resources Wales","keywords":"Induced pluripotent stem cell; SOX2; Stem cell; Biology; Embryonic stem cell; KLF4; Somatic cell; Adult stem cell; Cell biology; Cell potency; Reprogramming; Homeobox protein NANOG; Cellular differentiation; Induced stem cells; Cord blood; KOSR; Molecular biology; Immunology; Cell; Genetics; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003233939,0.0001885666,0.0001486416,0.0002451868,0.0001477297,0.0003455803,0.000139647,0.0001346887,0.001651499],"category_scores_gemma":[0.000224872,0.0001106789,0.0001847312,0.0002424322,0.0001574912,0.0001201619,0.0002271159,0.0003661369,0.0005234184],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000206881,"about_ca_system_score_gemma":0.0002841924,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005343187,"about_ca_topic_score_gemma":0.0006466176,"domain_scores_codex":[0.999871,0.00003274449,0.00002010323,0.00001798406,0.0000323714,0.00002561995],"domain_scores_gemma":[0.9998695,0.00003779746,0.00001491631,0.000036578,0.00002084172,0.00002037325],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002019962,0.00002483621,0.0003340766,0.00003331703,0.000004046427,0.00004768991,0.00003096185,0.0000482975,0.9949666,0.0004860428,0.00006408492,0.003758131],"study_design_scores_gemma":[0.00001985054,0.0001033428,0.001962804,0.000005453165,0.00001004755,0.000127636,0.00001469049,0.0002387017,0.9944905,0.00008382166,0.002941455,0.000001641379],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9814125,0.002647169,0.009076603,0.0001352076,0.00005493214,0.0001246745,0.0009928554,0.0001543311,0.005401595],"genre_scores_gemma":[0.9906047,0.0009140431,0.00339195,0.00005157118,0.00001611079,0.00003755488,0.001196141,0.0000384396,0.003749435],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001651499,"threshold_uncertainty_score":0.005524814,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0150941504601728,"score_gpt":0.2941643597314835,"score_spread":0.2790702092713107,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}