{"id":"W1971964490","doi":"10.1016/j.exphem.2010.05.009","title":"Induction of pluripotency in human cord blood unrestricted somatic stem cells","year":2010,"lang":"en","type":"article","venue":"Experimental Hematology","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":54,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Deutsche Forschungsgemeinschaft; Max-Planck-Gesellschaft; Stem Cell Network; Bundesministerium für Bildung und Forschung; Natural Resources Wales","keywords":"Induced pluripotent stem cell; SOX2; Stem cell; Biology; Embryonic stem cell; KLF4; Somatic cell; Adult stem cell; Cell biology; Cell potency; Reprogramming; Homeobox protein NANOG; Cellular differentiation; Induced stem cells; Cord blood; KOSR; Molecular biology; Immunology; Cell; Genetics; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001254953,0.000168362,0.0002705265,0.0001566898,0.00005499203,0.000007661048,0.0002797969,0.0002846569,0.0001000545],"category_scores_gemma":[0.00001155201,0.0001724255,0.00007071866,0.0001648721,0.0001894931,0.000006527846,0.0001835149,0.0002316778,0.00001845315],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001303506,"about_ca_system_score_gemma":0.00005525198,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000077442,"about_ca_topic_score_gemma":0.00005575096,"domain_scores_codex":[0.9986107,0.0001046225,0.0004114663,0.0003726322,0.0001716743,0.0003289432],"domain_scores_gemma":[0.9993178,0.00001566781,0.0001335126,0.000404091,0.00004399583,0.00008492026],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006538139,0.000575118,0.003130165,0.00004711141,0.00002676832,0.00002651275,0.00007242462,0.00000233902,0.9943057,0.001503725,0.0001032555,0.0001414575],"study_design_scores_gemma":[0.001106809,0.0005372385,0.0008234151,0.00001490667,0.000006130402,0.0001626493,0.0002569574,0.00002049536,0.9966433,0.0000493791,0.0002264425,0.0001522554],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9971882,0.001197454,0.00002025622,0.0000244562,0.0003051373,0.0003216693,0.00000598333,0.00001397641,0.0009228414],"genre_scores_gemma":[0.9991124,0.00002122658,0.000346687,0.00001465307,0.00005250028,0.00005176261,0.00003727384,0.00002414209,0.000339359],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00233758,"threshold_uncertainty_score":0.7031307,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0150941504601728,"score_gpt":0.2941643597314835,"score_spread":0.2790702092713107,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}