{"id":"W1971965533","doi":"10.1016/s0027-5107(01)00105-1","title":"Mutagenicity of TCDD in Big Blue® transgenic rats","year":2001,"lang":"en","type":"article","venue":"Mutation research. Fundamental and molecular mechanisms of mutagenesis","topic":"Carcinogens and Genotoxicity Assessment","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Victoria","funders":"","keywords":"Carcinogen; Transgene; Toxicity; Mutation; Genetically modified mouse; Chemistry; Toxicology; In vitro; Internal medicine; Biology; Endocrinology; Physiology; Biochemistry; Medicine; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002528411,0.0007098697,0.0003808331,0.002210388,0.0002780869,0.0002645878,0.0005457542,0.000760816,0.003701699],"category_scores_gemma":[0.0002663039,0.0004927287,0.0004402463,0.000550434,0.0005137794,0.0002525479,0.0003646744,0.0009638173,0.0008340768],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000506132,"about_ca_system_score_gemma":0.0003606602,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002890899,"about_ca_topic_score_gemma":0.002650623,"domain_scores_codex":[0.999648,0.00005274118,0.00002557274,0.0001010116,0.00009009644,0.00008252716],"domain_scores_gemma":[0.9993783,0.0001324456,0.0001954936,0.00007814655,0.00006377017,0.0001518097],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001662994,0.00003181141,0.0002409162,0.00001226447,0.000004973888,0.00004552309,0.00001515866,0.00004484879,0.9988513,0.0001112744,0.00003152799,0.0004441087],"study_design_scores_gemma":[0.00003298719,0.0003373736,0.003436425,0.000007851143,0.00003686007,0.0002393292,0.00002776751,0.0004212785,0.9945674,0.000110233,0.0007729154,0.000009548396],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9904901,0.0007259607,0.005225442,0.0002234979,0.00007422361,0.00002972252,0.001368582,0.0004424626,0.001419982],"genre_scores_gemma":[0.9778471,0.001214136,0.00272301,0.00009190087,0.00002447456,0.00007329926,0.002099664,0.0002026014,0.01572375],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003701699,"threshold_uncertainty_score":0.0123834,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03512896965796276,"score_gpt":0.3216941157231159,"score_spread":0.2865651460651532,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}