{"id":"W1971984883","doi":"10.1016/j.actbio.2008.02.027","title":"Modeling vancomycin release kinetics from microporous calcium phosphate ceramics comparing static and dynamic immersion conditions","year":2008,"lang":"en","type":"article","venue":"Acta Biomaterialia","topic":"Drug Solubulity and Delivery Systems","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":86,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University","funders":"","keywords":"Materials science; Microporous material; Polymer; Ceramic; Diffusion; Kinetics; Bioceramic; Chemical engineering; Drug delivery; Composite material; Controlled release; Biomedical engineering; Nanotechnology; Thermodynamics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001878183,0.0003018022,0.0004311529,0.00009260494,0.0004885092,0.00005718583,0.000205864,0.0003078904,0.000304522],"category_scores_gemma":[0.00001727996,0.0003168968,0.0000669881,0.000119628,0.0002613536,0.0001965582,0.0001370865,0.0002231798,0.0001570739],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000113273,"about_ca_system_score_gemma":0.00004547764,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001653196,"about_ca_topic_score_gemma":0.00007424631,"domain_scores_codex":[0.9981021,0.0003144063,0.0005615593,0.0004202538,0.0001428098,0.0004589193],"domain_scores_gemma":[0.999128,0.0001014514,0.0001635813,0.0002611594,0.00007901245,0.0002668278],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"simulation_or_modeling","study_design_scores_codex":[0.0004933832,0.0003222136,0.003326374,0.0001115994,0.0002049745,0.0001810011,0.002214449,0.003110674,0.9864216,0.00003766736,0.00336145,0.0002145475],"study_design_scores_gemma":[0.004579815,0.0001890348,0.00337137,0.0001048473,0.0003836919,0.0002391602,0.0008787985,0.8503565,0.1298975,0.000336171,0.008762391,0.0009007578],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9929319,0.0004201911,0.0008726726,0.0002704849,0.004170172,0.000347036,0.0007120655,0.0001467982,0.0001286641],"genre_scores_gemma":[0.9973572,0.0005496425,0.000365627,0.0005487864,0.0001457223,0.00001704688,0.0007589661,0.0000386779,0.0002183555],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.8565242,"threshold_uncertainty_score":0.9999283,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1043928544279775,"score_gpt":0.379284436311343,"score_spread":0.2748915818833655,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}