{"id":"W1971988052","doi":"10.1016/j.cellsig.2013.02.020","title":"Control of ALK (wild type and mutated forms) phosphorylation: Specific role of the phosphatase PTP1B","year":2013,"lang":"en","type":"article","venue":"Cellular Signalling","topic":"Neuroblastoma Research and Treatments","field":"Medicine","cited_by":12,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University","funders":"Université Pierre et Marie Curie; Institut National de la Santé et de la Recherche Médicale","keywords":"Protein tyrosine phosphatase; Receptor tyrosine kinase; Tyrosine phosphorylation; Biology; Phosphorylation; Proto-oncogene tyrosine-protein kinase Src; Tyrosine kinase; Cell biology; ROR1; Biochemistry; Cancer research; Signal transduction; Platelet-derived growth factor receptor; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009075284,0.0001015278,0.0002111556,0.00004365828,0.00005201409,0.00001129219,0.00007650066,0.00004241115,0.0003402288],"category_scores_gemma":[0.0000367854,0.00006603537,0.00005916207,0.0002116743,0.00009795334,0.00006561023,0.00002898606,0.0001131724,0.00003466984],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001588649,"about_ca_system_score_gemma":0.00004938389,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005579819,"about_ca_topic_score_gemma":8.631319e-7,"domain_scores_codex":[0.9991605,0.00002974619,0.0002235044,0.0001504051,0.0002588352,0.0001769822],"domain_scores_gemma":[0.999301,0.00007321499,0.0001024213,0.0002082996,0.0002083345,0.0001067467],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003094288,0.0001754714,0.007782404,0.00007048329,0.0001374398,0.0000270415,0.0001062858,0.00006367746,0.9862854,0.0004734038,0.0001081572,0.004460807],"study_design_scores_gemma":[0.002115673,0.0003047759,0.003436816,0.00009441053,0.00005834737,0.000008624384,0.00006960632,0.00309337,0.9895959,0.0004039298,0.0007617205,0.00005680742],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9906824,0.007645132,0.0003660994,0.00009971234,0.00003753365,0.0006342347,0.00001141831,0.00001218644,0.0005112425],"genre_scores_gemma":[0.9995089,0.0001070303,0.0001275883,0.00003456004,0.00002255581,0.000009520626,0.00002071541,0.00001561502,0.0001535337],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00882644,"threshold_uncertainty_score":0.3725266,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009992262009483948,"score_gpt":0.2169792943974951,"score_spread":0.2069870323880112,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}