{"id":"W1972071009","doi":"10.3748/wjg.v18.i44.6420","title":"Glucose-responsive artificial promoter-mediated insulin gene transfer improves glucose control in diabetic mice","year":2012,"lang":"en","type":"article","venue":"World Journal of Gastroenterology","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Calgary General Hospital; University of Calgary","funders":"","keywords":"Insulin; Internal medicine; Endocrinology; Islet; Genetic enhancement; Recombinant DNA; Diabetes mellitus; Gene expression; Biology; Medicine; Gene; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002819556,0.000814624,0.0005462072,0.0004633775,0.0001031799,0.0003600248,0.0003445364,0.0004754555,0.001334128],"category_scores_gemma":[0.0001136668,0.0002000686,0.0003656582,0.0002359562,0.0002888661,0.0003856244,0.0001743371,0.001122835,0.0003302777],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002505837,"about_ca_system_score_gemma":0.0002020568,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002211883,"about_ca_topic_score_gemma":0.0002672299,"domain_scores_codex":[0.9997519,0.00003247186,0.0000308847,0.00007214895,0.00006759879,0.00004511161],"domain_scores_gemma":[0.9998139,0.000013763,0.00009253195,0.0000179723,0.0000126302,0.00004926526],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003629552,0.0001488696,0.0001122025,0.00004975719,0.000007035177,0.00002340959,0.00000816628,0.00005531822,0.9975047,0.00005447472,0.00003157678,0.001641613],"study_design_scores_gemma":[0.0002170315,0.002501208,0.002887124,0.00002104791,0.00005556883,0.0002660785,0.00002741614,0.001137233,0.9901977,0.00005087013,0.002628624,0.000009982183],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9875678,0.002154739,0.008010474,0.0002164733,0.0001215663,0.00007344608,0.0004689232,0.0003095471,0.001076967],"genre_scores_gemma":[0.9718094,0.003786046,0.01667224,0.0002491302,0.00007099703,0.0002289449,0.001529006,0.0001859141,0.00546838],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001334128,"threshold_uncertainty_score":0.004463136,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01125636009764574,"score_gpt":0.2377695745423984,"score_spread":0.2265132144447526,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}