{"id":"W1972150222","doi":"10.1016/j.jaci.2005.01.042","title":"Leukotriene D4 Induces IL-8 Gene Transcription through CysLT1 Receptor Signalling: Involvement of AP-1 and NF-kB Binding Elements and Cdc42 Small G-protein","year":2005,"lang":"en","type":"article","venue":"Journal of Allergy and Clinical Immunology","topic":"IL-33, ST2, and ILC Pathways","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Sherbrooke","funders":"","keywords":"Signalling; Chemistry; CDC42; Transcription (linguistics); Transcription factor; Gene; Cell biology; Molecular biology; Biology; Signal transduction; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002542296,0.0005451943,0.0003218428,0.0005452636,0.0003440123,0.0004160512,0.0002158257,0.000351124,0.002560772],"category_scores_gemma":[0.0002523311,0.0002813425,0.0005982147,0.0002280018,0.0003590014,0.0002582198,0.0003640226,0.000666832,0.0006842046],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006408481,"about_ca_system_score_gemma":0.0004137018,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001295861,"about_ca_topic_score_gemma":0.002015378,"domain_scores_codex":[0.9996532,0.00008209366,0.00002790702,0.00003853509,0.00006064729,0.0001376424],"domain_scores_gemma":[0.9997666,0.00005345356,0.00004346846,0.00003765557,0.00003497399,0.00006384485],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001596592,0.0001119843,0.0005483276,0.00004969924,0.00001022272,0.0002118782,0.00004243622,0.00006414018,0.9954997,0.0002084076,0.0001068736,0.001549718],"study_design_scores_gemma":[0.0001888555,0.0004780914,0.0200444,0.00001392349,0.00004077554,0.0003079374,0.0001397666,0.0008361831,0.9761137,0.0002275138,0.001600673,0.000008237934],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9949149,0.001268102,0.001457372,0.0002441109,0.0000627386,0.00003337082,0.0003934566,0.0001000661,0.001525956],"genre_scores_gemma":[0.992359,0.0006066877,0.00103134,0.00009491765,0.00003069986,0.00006658024,0.0008514054,0.00001833524,0.004940975],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002560772,"threshold_uncertainty_score":0.008566618,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0565610367862496,"score_gpt":0.2868200952829574,"score_spread":0.2302590584967078,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}