{"id":"W1972170949","doi":"10.1159/000322817","title":"RNA Interference in Mammalian Cell Systems","year":2011,"lang":"en","type":"review","venue":"Hormone Research in Paediatrics","topic":"MicroRNA in disease regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Nutrition, Metabolism and Diabetes","funders":"Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung","keywords":"Biology; Trans-acting siRNA; RNA interference; microRNA; RNA; Gene silencing; Genetics; Small interfering RNA; RNA silencing; Gene; Computational biology; Long non-coding RNA; RasiRNA; Genome; Argonaute; Small RNA","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008051992,0.0008663182,0.001403093,0.001046522,0.0004739474,0.001377032,0.001212404,0.001166477,0.003988973],"category_scores_gemma":[0.000402684,0.0004046545,0.0005881282,0.001139223,0.001005034,0.0009328084,0.0008386665,0.001582402,0.00645634],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008965574,"about_ca_system_score_gemma":0.0005107669,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007131644,"about_ca_topic_score_gemma":0.0008191539,"domain_scores_codex":[0.9993646,0.0001374096,0.00006789889,0.0001284191,0.0002577504,0.00004393466],"domain_scores_gemma":[0.9998323,0.00007327307,0.00002556136,0.00002157666,0.00003513673,0.00001220832],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001149207,0.00007158206,0.0002643274,0.009570685,0.0001259004,0.001112259,0.0003731266,0.0009001091,0.2346439,0.05151592,0.03188508,0.6694223],"study_design_scores_gemma":[0.0000123999,0.00007342431,0.0003398546,0.0003471439,0.00003645378,0.00116509,0.0000348475,0.0001596509,0.03201271,0.002858807,0.9629352,0.00002435768],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00186077,0.9313133,0.0210455,0.0008611842,0.001486171,0.0001414111,0.0004771553,0.0005007519,0.04231377],"genre_scores_gemma":[0.02934538,0.9260477,0.02108693,0.001611771,0.0007391803,0.0005254526,0.00105145,0.0001082207,0.01948384],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003988973,"threshold_uncertainty_score":0.01334447,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1021580841476646,"score_gpt":0.3649446718467071,"score_spread":0.2627865876990426,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}