{"id":"W1972189052","doi":"10.1074/jbc.m110649200","title":"Macrophages Inhibit Salmonella Typhimurium Replication through MEK/ERK Kinase and Phagocyte NADPH Oxidase Activities","year":2002,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Phagocytosis and Immune Regulation","field":"Immunology and Microbiology","cited_by":104,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research; Michael Smith Health Research BC","keywords":"Phagocyte; NADPH oxidase; MAPK/ERK pathway; Salmonella; Microbiology; Replication (statistics); Kinase; Chemistry; Cell biology; Biology; Phagocytosis; Virology; Reactive oxygen species; Bacteria; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002630516,0.0001949025,0.0003775427,0.00002795106,0.0001427545,0.00002672779,0.0001765947,0.0003727437,0.0008105779],"category_scores_gemma":[0.000201917,0.0001380761,0.0001433995,0.00009395376,0.0003311339,0.0001808894,0.00007869311,0.0003935348,0.00002526851],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005338503,"about_ca_system_score_gemma":0.00001451667,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003525708,"about_ca_topic_score_gemma":9.943619e-8,"domain_scores_codex":[0.9988459,0.0001005667,0.0004924009,0.0002655388,0.00005347815,0.000242069],"domain_scores_gemma":[0.9989903,0.0001387745,0.0004840072,0.0002579156,0.00008973357,0.00003926735],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001600071,0.0001564645,0.0006091588,0.00002624493,0.0000841622,0.00001579729,0.00009672656,0.000001810578,0.9916699,0.00002642064,0.00178654,0.00536679],"study_design_scores_gemma":[0.0009823114,0.0002043366,0.004010543,0.00004844536,0.00003773218,0.0007269768,0.0001207632,0.000007136498,0.9807029,0.0002764059,0.01271655,0.0001658818],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9747007,0.02329942,0.00005377682,0.0004601887,0.0001297293,0.00006842469,0.00001478841,0.0000253889,0.001247611],"genre_scores_gemma":[0.9958501,0.002479496,0.0001435243,0.0001247054,0.0001361835,0.000004176774,0.00002072748,0.000009835931,0.001231213],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02114947,"threshold_uncertainty_score":0.887526,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03138609704943342,"score_gpt":0.2503726575442453,"score_spread":0.2189865604948119,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}