{"id":"W1972189052","doi":"10.1074/jbc.m110649200","title":"Macrophages Inhibit Salmonella Typhimurium Replication through MEK/ERK Kinase and Phagocyte NADPH Oxidase Activities","year":2002,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Phagocytosis and Immune Regulation","field":"Immunology and Microbiology","cited_by":104,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research; Michael Smith Health Research BC","keywords":"Phagocyte; NADPH oxidase; MAPK/ERK pathway; Salmonella; Microbiology; Replication (statistics); Kinase; Chemistry; Cell biology; Biology; Phagocytosis; Virology; Reactive oxygen species; Bacteria; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000143863,0.000330898,0.0001753126,0.00009466054,0.00008099266,0.0001400768,0.0001290374,0.0001207467,0.0007474269],"category_scores_gemma":[0.00008488823,0.0001060336,0.0002484316,0.00003649938,0.0001205089,0.0001213836,0.0001395694,0.0003217775,0.0002318044],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001276037,"about_ca_system_score_gemma":0.0002081763,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003120852,"about_ca_topic_score_gemma":0.0007672028,"domain_scores_codex":[0.9998991,0.00002166111,0.000008171057,0.00001316655,0.00001913591,0.00003858455],"domain_scores_gemma":[0.9999435,0.000009119912,0.00001741789,0.000005664065,0.000009913572,0.00001436176],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000312039,0.0000344367,0.0001901612,0.00004455378,0.000003612477,0.00002163284,0.000007574631,0.00002788025,0.997863,0.00003794977,0.00003551995,0.001421767],"study_design_scores_gemma":[0.00002901153,0.0005667059,0.006143435,0.00000698924,0.00001660376,0.0001357699,0.00002167354,0.0006172766,0.9908571,0.00003946517,0.001562999,0.000002910155],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9952022,0.001966591,0.001650792,0.0001008022,0.00002760442,0.00002422265,0.0001158661,0.00005611138,0.000855896],"genre_scores_gemma":[0.9951131,0.0008984842,0.001799084,0.00004394693,0.00001081033,0.00003596266,0.0001527979,0.000008339776,0.001937566],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007474269,"threshold_uncertainty_score":0.002500355,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03138609704943342,"score_gpt":0.2503726575442453,"score_spread":0.2189865604948119,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}