{"id":"W1972189514","doi":"10.1021/ol052081f","title":"Uncialamycin, A New Enediyne Antibiotic","year":2005,"lang":"en","type":"article","venue":"Organic Letters","topic":"Plant and fungal interactions","field":"Agricultural and Biological Sciences","cited_by":157,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Enediyne; Antibiotics; Microbiology; Chemistry; Burkholderia; Antibacterial activity; In vitro; Human pathogen; Burkholderia cepacia complex; Bacteria; Stereochemistry; Biology; Biochemistry; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.00003971433,0.00007831303,0.00007668182,0.000006961055,0.00009201354,0.00004173889,0.0001319498,0.00003722159,0.00188275],"category_scores_gemma":[0.00002021402,0.00002968169,0.00004570685,0.0001619932,0.00001300324,0.0001298852,0.00002243666,0.00008896136,0.001130724],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003093944,"about_ca_system_score_gemma":0.000006062686,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001298005,"about_ca_topic_score_gemma":0.001045877,"domain_scores_codex":[0.9994755,0.00001322408,0.00009475153,0.000142313,0.00009193009,0.0001823085],"domain_scores_gemma":[0.9997878,0.00005826833,0.00003018636,0.00003099234,0.000009446595,0.00008329334],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000003596536,0.00002789926,0.0008690262,3.609017e-7,0.000005412484,0.000003089785,0.00002952401,5.623902e-7,0.924787,0.00003151426,0.05796687,0.01627513],"study_design_scores_gemma":[0.0003789768,0.000100595,0.07398839,0.00002573131,0.00003187699,0.00008537708,0.0000821794,0.00004851274,0.3945121,0.00004241236,0.5302988,0.0004050349],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9552595,0.00003980571,0.00001328776,0.04359053,0.0001956177,0.00004566064,0.00000798397,0.00007866226,0.0007689496],"genre_scores_gemma":[0.9905244,0.00001511171,0.0001040432,0.0070152,0.001461871,3.304765e-7,0.00002526958,7.041168e-7,0.0008530783],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5302749,"threshold_uncertainty_score":0.999647,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01364980929516319,"score_gpt":0.1944420338870793,"score_spread":0.1807922245919161,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}