{"id":"W1972215954","doi":"10.1016/j.ymgme.2009.04.005","title":"Processing of alkylcobalamins in mammalian cells: A role for the MMACHC (cblC) gene product","year":2009,"lang":"en","type":"article","venue":"Molecular Genetics and Metabolism","topic":"Folate and B Vitamins Research","field":"Medicine","cited_by":132,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University","funders":"National Heart, Lung, and Blood Institute; National Institutes of Health","keywords":"Adenosylcobalamin; Complementation; Hydroxocobalamin; Methylcobalamin; Chemistry; Mutant; Biochemistry; Gene product; Molecular biology; Biology; Gene; Genetics; Cobalamin; Vitamin B12; Cyanocobalamin; Gene expression","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002259815,0.000393425,0.0004023672,0.0002718968,0.0003301719,0.001072396,0.0003087007,0.0005558703,0.0009537789],"category_scores_gemma":[0.0002613672,0.0002170551,0.0003312553,0.0002162975,0.0004432217,0.0006653179,0.0003803411,0.000842428,0.0007601489],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001061234,"about_ca_system_score_gemma":0.0004937685,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003707619,"about_ca_topic_score_gemma":0.002704519,"domain_scores_codex":[0.9998733,0.0000128935,0.00001246823,0.00003579937,0.00003429817,0.00003120172],"domain_scores_gemma":[0.9998043,0.00003063656,0.00003416311,0.00004142103,0.00005093465,0.00003855412],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001545187,0.000004208204,0.000236232,0.00002157949,0.000003127495,0.0001122157,0.00002243952,0.00002939794,0.9982321,0.0002251733,0.0000335622,0.0009256146],"study_design_scores_gemma":[0.000009295704,0.00004733231,0.005179109,0.000007561715,0.00001101659,0.0004927089,0.00008303688,0.0003308359,0.9915741,0.0001641179,0.002093309,0.000007518212],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9749706,0.009178311,0.01130458,0.0009914329,0.00008528093,0.00003549012,0.0006390882,0.0002194815,0.00257573],"genre_scores_gemma":[0.9818835,0.002441861,0.008503641,0.000182607,0.00002442428,0.00002751275,0.001447527,0.00006382811,0.005425004],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003707619,"threshold_uncertainty_score":0.007699788,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01334574051525248,"score_gpt":0.2827238771504784,"score_spread":0.2693781366352259,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}