{"id":"W1972307586","doi":"10.1074/jbc.m108757200","title":"The Anti-inflammatory Cytokine, Interleukin (IL)-10, Blocks the Inhibitory Effect of IL-1β on Long Term Potentiation","year":2001,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Neuroinflammation and Neurodegeneration Mechanisms","field":"Neuroscience","cited_by":138,"is_retracted":false,"has_abstract":true,"ca_institutions":"Trinity College","funders":"European Commission; Higher Education Authority; Enterprise Ireland; Health Research Board","keywords":"Long-term potentiation; Proinflammatory cytokine; Cytokine; Perforant path; Biology; Chemistry; Endocrinology; Receptor; Internal medicine; Immunology; Inflammation; Medicine; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001190814,0.0005190505,0.000318748,0.0001577994,0.00007511071,0.0002331385,0.0002884719,0.0002333573,0.001653132],"category_scores_gemma":[0.0001436788,0.0001517968,0.0002318055,0.00009252148,0.0002480363,0.0001972672,0.0001364458,0.000877878,0.0005270525],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001501943,"about_ca_system_score_gemma":0.0003506903,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003761503,"about_ca_topic_score_gemma":0.0007387031,"domain_scores_codex":[0.9998822,0.00001970613,0.0000117324,0.00001273437,0.00002200299,0.00005165116],"domain_scores_gemma":[0.9998912,0.00002554671,0.00002482695,0.000009187147,0.00001065448,0.00003866266],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005787064,0.0002080149,0.0001659697,0.0001388528,0.00001266795,0.000108987,0.00001211722,0.00008331135,0.9927817,0.00007663256,0.0001077921,0.005725207],"study_design_scores_gemma":[0.000191706,0.004389133,0.006978851,0.00002900086,0.00004875986,0.0007123576,0.0000264177,0.0008176279,0.9824275,0.0001524518,0.00421771,0.000008485008],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9821211,0.0110152,0.002726796,0.0002867019,0.0002885562,0.00006267866,0.0002647345,0.0001173071,0.003117008],"genre_scores_gemma":[0.9832274,0.01014093,0.003057271,0.0002103868,0.00008978532,0.00007051593,0.0005068001,0.00001907106,0.002677729],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001653132,"threshold_uncertainty_score":0.005530298,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01939003111397465,"score_gpt":0.2508633275160003,"score_spread":0.2314732964020256,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}