{"id":"W1972406166","doi":"10.4161/onci.27156","title":"An allogeneic NK cell line engineered to express chimeric antigen receptors","year":2013,"lang":"en","type":"article","venue":"OncoImmunology","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Institute of Cancer Research; Labex Immuno-Oncology; Institut National Du Cancer; Ligue Contre le Cancer; Agence Nationale de la Recherche","keywords":"Cytotoxic T cell; Chimeric antigen receptor; Antigen; Interleukin 21; NK-92; Biology; Antibody; Antibody-dependent cell-mediated cytotoxicity; Adoptive cell transfer; Immunology; Natural killer T cell; Immunotherapy; Cancer research; T cell; Monoclonal antibody; Immune system; CD8; In vitro","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000156958,0.0004201911,0.0005487415,0.000236585,0.0001414451,0.0004713705,0.0003868656,0.000477857,0.001899783],"category_scores_gemma":[0.0001615863,0.0001537672,0.0002608133,0.0002180091,0.0001939879,0.0002805834,0.000262678,0.001376324,0.001441629],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002982458,"about_ca_system_score_gemma":0.0002190075,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003568398,"about_ca_topic_score_gemma":0.0002847424,"domain_scores_codex":[0.999675,0.00003746994,0.00004832471,0.00008230083,0.0001049686,0.00005189366],"domain_scores_gemma":[0.9998922,0.00001994132,0.00001852354,0.00002926927,0.00001709496,0.00002301219],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002110133,0.0001430105,0.0002743563,0.00004749318,0.00001052598,0.0002128012,0.00003073434,0.0004531153,0.9949186,0.0005890488,0.000196207,0.002912987],"study_design_scores_gemma":[0.0001609921,0.0006953564,0.00104717,0.0000137152,0.00005627083,0.001770531,0.00002887117,0.006454467,0.9730178,0.0001579582,0.01658334,0.00001351853],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9597417,0.00256951,0.02339591,0.0003743151,0.0004816045,0.0002380168,0.002183821,0.0005785959,0.01043663],"genre_scores_gemma":[0.9841596,0.0007757146,0.007648727,0.0001040453,0.00002969163,0.0001294239,0.001687264,0.00006480427,0.005400749],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001899783,"threshold_uncertainty_score":0.006355405,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01922988873651518,"score_gpt":0.2991261395650586,"score_spread":0.2798962508285434,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}