{"id":"W1972441542","doi":"10.1073/pnas.97.12.6311","title":"Solution structure of the RNA polymerase subunit RPB5 from <i>Methanobacterium thermoautotrophicum</i>","year":2000,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Enzyme Structure and Function","field":"Materials Science","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Ontario Institute for Cancer Research","funders":"","keywords":"Protein subunit; Transcription (linguistics); Thermophile; Polymerase; RNA polymerase; RNA; Biology; Transcription factor II D; Activator (genetics); Biochemistry; Chemistry; Crystallography; Cell biology; Biophysics; Gene; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004640674,0.0001188598,0.0001716998,0.0000654241,0.0002633934,0.00002829029,0.001027431,0.0001184884,0.0007416718],"category_scores_gemma":[0.000147094,0.00006324569,0.0000986455,0.00064783,0.001048398,0.0004878004,0.0001048108,0.0001682561,0.000002379242],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002573341,"about_ca_system_score_gemma":0.00004482975,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009686825,"about_ca_topic_score_gemma":7.035908e-7,"domain_scores_codex":[0.9980593,0.00002234747,0.0003627604,0.0002486614,0.001141688,0.0001652014],"domain_scores_gemma":[0.9991571,0.00007485459,0.0005221365,0.00002285922,0.0001955209,0.00002755884],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003264074,0.00001334205,0.0007740665,0.00001588183,0.000006184093,1.578926e-9,0.0001902026,0.00007412979,0.9954188,0.002652231,0.000249529,0.0005729538],"study_design_scores_gemma":[0.0001260186,0.0000261328,0.06466375,0.00005003345,0.0000193295,0.000003398912,0.00004144845,0.0001243647,0.9047543,0.02999893,0.0001260013,0.00006625771],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9947647,0.0001270593,8.496755e-7,0.001610047,0.0001134892,0.0001319927,0.0001418773,0.00001234958,0.003097647],"genre_scores_gemma":[0.9987781,0.00001604011,0.0004877889,0.0003522456,0.0001777767,0.000002026089,3.97666e-7,0.000004764186,0.0001808651],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0906645,"threshold_uncertainty_score":0.8120786,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01775369972015414,"score_gpt":0.2469681137945542,"score_spread":0.2292144140744001,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}