{"id":"W1972463305","doi":"10.1186/1758-2652-13-s4-p227","title":"Therapeutics designed to neutralize soluble HIV tat protein could preserve IL‐7 signaling and CD8 T‐cell function in HIV+ patients","year":2010,"lang":"en","type":"article","venue":"Journal of the International AIDS Society","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ottawa Hospital","funders":"","keywords":"Medicine; Human immunodeficiency virus (HIV); CD8; T cell; Cytotoxic T cell; Virology; Immunology; Pharmacology; Immune system; Biochemistry; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001979045,0.0002416589,0.0003213508,0.0001176792,0.0002399347,0.0004127353,0.0001414648,0.0004511106,0.002615497],"category_scores_gemma":[0.0001659805,0.00009588052,0.0001920958,0.00004992714,0.0002719106,0.0001709691,0.0001247522,0.0007364886,0.0004798122],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001847407,"about_ca_system_score_gemma":0.0002058115,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001699294,"about_ca_topic_score_gemma":0.0004494243,"domain_scores_codex":[0.9999365,0.00001521208,0.000005347628,0.000007068596,0.00001338093,0.00002250965],"domain_scores_gemma":[0.9999638,0.00001095439,0.000006662981,0.000002766433,0.000006462813,0.000009462711],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.006156383,0.001692952,0.002623156,0.0003055283,0.00009979501,0.001019201,0.0001887214,0.001161962,0.790711,0.002851474,0.006473497,0.1867163],"study_design_scores_gemma":[0.004488892,0.0581228,0.01581428,0.0001209357,0.0003523995,0.004947529,0.0001264513,0.003324038,0.8152058,0.0012971,0.09615081,0.00004903641],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9777988,0.009625589,0.002272131,0.001734258,0.0009478979,0.0002321887,0.00009474799,0.0001839086,0.007110418],"genre_scores_gemma":[0.9840957,0.003778159,0.001579485,0.000760217,0.0002625722,0.00008125151,0.00018904,0.00001764595,0.009235932],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002615497,"threshold_uncertainty_score":0.008749783,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01611764160245186,"score_gpt":0.2581125524001436,"score_spread":0.2419949107976917,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}