{"id":"W1972623951","doi":"10.1016/j.virol.2008.04.022","title":"Reduction in intracellular HCV RNA and virus protein expression in human hepatoma cells following treatment with 2′-O-methyl-modified anti-core deoxyribozyme","year":2008,"lang":"en","type":"article","venue":"Virology","topic":"Hepatitis C virus research","field":"Medicine","cited_by":11,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Montréal","funders":"Canadian Institutes of Health Research; Health Canada; National Institutes of Health","keywords":"RNA; Biology; Virology; Deoxyribozyme; Intracellular; Hepatitis C virus; DNA; Molecular biology; Virus; Gene; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001617076,0.0002126684,0.0003096927,0.0001053189,0.0001647478,0.0002424953,0.0001370288,0.0002502894,0.001175617],"category_scores_gemma":[0.0001685793,0.0001567701,0.0002832407,0.0001434188,0.0002073834,0.0001606267,0.0001049324,0.0003735165,0.0003308901],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001978832,"about_ca_system_score_gemma":0.000177409,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001214976,"about_ca_topic_score_gemma":0.001024726,"domain_scores_codex":[0.9998894,0.00002462497,0.00001071658,0.00002107786,0.00002006177,0.00003417951],"domain_scores_gemma":[0.999893,0.00004408847,0.00001252578,0.00001752342,0.00001665633,0.00001621466],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003075339,0.00001845052,0.0001066274,0.00001620012,0.000003362336,0.00003099356,0.00002283497,0.00002794543,0.9989279,0.00003878717,0.0000205052,0.0004788243],"study_design_scores_gemma":[0.00001772864,0.000319688,0.002756116,0.000001494779,0.00001072757,0.00007160596,0.00001745228,0.0003567003,0.9959402,0.00001625945,0.000489836,0.000002317313],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.99635,0.0008091778,0.001219903,0.00005179076,0.00003889699,0.00001626534,0.0002378667,0.0000352516,0.001240856],"genre_scores_gemma":[0.99615,0.000272666,0.0009470116,0.00002832106,0.00001511042,0.00002318875,0.0005008712,0.00001311621,0.002049775],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001214976,"threshold_uncertainty_score":0.003932834,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04320391019794734,"score_gpt":0.3093359770489957,"score_spread":0.2661320668510483,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}