{"id":"W1972639501","doi":"10.1099/mic.0.033605-0","title":"SanG, a transcriptional activator, controls nikkomycin biosynthesis through binding to the sanN–sanO intergenic region in Streptomyces ansochromogenes","year":2009,"lang":"en","type":"article","venue":"Microbiology","topic":"Microbial Natural Products and Biosynthesis","field":"Medicine","cited_by":31,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Natural Science Foundation of China; Ministry of Science and Technology of the People's Republic of China; Chinese Academy of Sciences; University of Alberta","keywords":"GTP'; GTPase; Electrophoretic mobility shift assay; Biology; Transcription (linguistics); DNA footprinting; Biochemistry; Molecular biology; Gene; Mutant; ATPase; Promoter; Transcription factor; Enzyme; Gene expression","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002874356,0.0002954625,0.000539026,0.0002069557,0.0001303888,0.00002581678,0.000278378,0.0002538451,0.000384475],"category_scores_gemma":[0.0001730348,0.0001832033,0.0002112397,0.000454031,0.0001208508,0.00009991495,0.0000347495,0.000291888,0.0001045486],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001571919,"about_ca_system_score_gemma":0.00007582339,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009246188,"about_ca_topic_score_gemma":0.0001522245,"domain_scores_codex":[0.9981481,0.0001930708,0.0004419962,0.0005887117,0.00006952984,0.0005585441],"domain_scores_gemma":[0.9992529,0.0001240089,0.000105713,0.0003678109,0.00006946416,0.00008007158],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005942231,0.0001605568,0.0007928222,0.00001685818,0.00008222894,0.00002872147,0.0005085202,0.000001803067,0.9803714,0.0001257506,0.009523246,0.007793925],"study_design_scores_gemma":[0.0008984148,0.0004587797,0.006386795,0.0001869062,0.00007743832,0.0004177302,0.0002352029,0.000002118225,0.8396957,0.00005025318,0.1513365,0.0002541733],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9576436,0.001885957,0.00005353691,0.03901085,0.0003250495,0.0007363592,0.00007245052,0.00005868644,0.0002134749],"genre_scores_gemma":[0.9933436,0.0002210172,0.0005270322,0.004865648,0.0003985228,0.000006067277,0.00006195284,0.00001874117,0.0005574065],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1418133,"threshold_uncertainty_score":0.7470815,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02134670493387927,"score_gpt":0.2640325317150521,"score_spread":0.2426858267811728,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}