{"id":"W1972659294","doi":"10.1016/s0304-3959(02)00097-0","title":"Partial sciatic nerve ligation induces increase in the phosphorylation of extracellular signal-regulated kinase (ERK) and c-Jun N-terminal kinase (JNK) in astrocytes in the lumbar spinal dorsal horn and the gracile nucleus","year":2002,"lang":"en","type":"article","venue":"Pain","topic":"Pain Mechanisms and Treatments","field":"Medicine","cited_by":202,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Canadian Institutes of Health Research; McGill University","keywords":"Sciatic nerve; MAPK/ERK pathway; Cell biology; Neuropathic pain; Sciatic nerve injury; Kinase; Protein kinase A; Chemistry; Signal transduction; Neuroscience; Biology; Anatomy","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004827483,0.0001794863,0.0002779274,0.0001397993,0.0001010451,0.00004674738,0.0001081159,0.00009136336,0.00003728836],"category_scores_gemma":[0.0004016523,0.0001006867,0.00004679291,0.0003910621,0.0001818705,0.0001111797,0.0000256312,0.0002505741,0.000002360431],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004726879,"about_ca_system_score_gemma":0.00002458613,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001047393,"about_ca_topic_score_gemma":0.0002383663,"domain_scores_codex":[0.9972439,0.001545721,0.0004006344,0.0002404281,0.0003286282,0.0002407004],"domain_scores_gemma":[0.9991136,0.0004387255,0.0001602862,0.0002133077,0.00002789561,0.00004618045],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.007347536,0.007425567,0.299329,0.0009097201,0.0002988131,0.005754283,0.08172079,0.0004332724,0.1601428,0.006371786,0.0001974797,0.4300689],"study_design_scores_gemma":[0.02193856,0.002425292,0.6658713,0.001348848,0.0004312273,0.0002266421,0.009199329,0.2666663,0.02719517,0.004099281,0.0001051516,0.0004929156],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9955257,0.00267941,0.0001095357,0.0007529522,0.00001598579,0.0008640655,0.000005379768,0.000008536567,0.00003843757],"genre_scores_gemma":[0.9994655,0.00007613604,0.0001425936,0.0001368987,0.00003839013,0.0000961223,0.00001896195,0.00001113579,0.00001422779],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.429576,"threshold_uncertainty_score":0.4105885,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01561685025070968,"score_gpt":0.2356184266199723,"score_spread":0.2200015763692626,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}