{"id":"W1972710782","doi":"10.1039/c3an01540h","title":"Single-channel electrophysiology of cell-free expressed ion channels by direct incorporation in lipid bilayers","year":2013,"lang":"en","type":"article","venue":"The Analyst","topic":"Ion channel regulation and function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université du Québec à Montréal","funders":"Engineering and Physical Sciences Research Council","keywords":"Electrophysiology; Ion channel; Lipid bilayer; Biophysics; Chemistry; Channel (broadcasting); Membrane potential; Membrane; Biochemistry; Biology; Neuroscience; Computer science; Telecommunications","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004894177,0.0003735557,0.0003935476,0.0001786032,0.000224374,0.0005481095,0.0005157507,0.0003454993,0.0006305405],"category_scores_gemma":[0.0006473319,0.00017592,0.0002116314,0.0001789071,0.0004735225,0.0006784597,0.0003972869,0.0008347772,0.0004454135],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003507406,"about_ca_system_score_gemma":0.0002292089,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003700986,"about_ca_topic_score_gemma":0.000565311,"domain_scores_codex":[0.9996939,0.00004730828,0.0000342495,0.00006482167,0.0001279395,0.00003177527],"domain_scores_gemma":[0.9995221,0.0002292025,0.00007237023,0.00006366485,0.00006297333,0.00004965236],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001499031,0.000003912072,0.00003851599,0.00001195678,0.000001647279,0.000007910376,0.000009929511,0.00002167789,0.9996389,0.0000466429,0.000006473721,0.000197369],"study_design_scores_gemma":[0.000003794651,0.0000180746,0.0002741879,0.000001730479,0.000003057235,0.00003102,0.00001058513,0.0008258696,0.9985594,0.00004307502,0.00022663,0.000002584738],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9410085,0.00043162,0.05640506,0.0001806663,0.00005022853,0.00008789248,0.0006221245,0.000332643,0.000881217],"genre_scores_gemma":[0.9401757,0.0009412813,0.05636598,0.00007747801,0.00001938665,0.0001671823,0.0006009558,0.00012131,0.001530756],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006305405,"threshold_uncertainty_score":0.002588272,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0098776555937281,"score_gpt":0.2005460525987634,"score_spread":0.1906683970050353,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}