{"id":"W1972710782","doi":"10.1039/c3an01540h","title":"Single-channel electrophysiology of cell-free expressed ion channels by direct incorporation in lipid bilayers","year":2013,"lang":"en","type":"article","venue":"The Analyst","topic":"Ion channel regulation and function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université du Québec à Montréal","funders":"Engineering and Physical Sciences Research Council","keywords":"Electrophysiology; Ion channel; Lipid bilayer; Biophysics; Chemistry; Channel (broadcasting); Membrane potential; Membrane; Biochemistry; Biology; Neuroscience; Computer science; Telecommunications","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000142979,0.0001127953,0.0001495889,0.00008112346,0.00004821741,0.00001320818,0.0001797276,0.0001173643,0.00003472253],"category_scores_gemma":[0.00003967982,0.00008416778,0.00007259801,0.000213061,0.00005769266,0.000009102667,0.0000573434,0.00005911671,0.00001233892],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001607463,"about_ca_system_score_gemma":0.00001726674,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001751534,"about_ca_topic_score_gemma":0.00002498118,"domain_scores_codex":[0.9991741,0.0001236898,0.0002302218,0.0002139791,0.0000986919,0.0001593191],"domain_scores_gemma":[0.9993414,0.00001638801,0.000163408,0.0003477553,0.0001000961,0.00003096723],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006592249,0.00007523782,0.00004764081,0.000006801096,0.00001717104,9.115661e-8,0.00005560973,0.002216352,0.9873604,0.00001160364,0.009936412,0.0002067743],"study_design_scores_gemma":[0.0004403552,0.0003029331,0.0002694064,0.000005550288,0.00001232495,6.646206e-7,0.0001135748,0.003785457,0.9925294,0.0004012405,0.002030485,0.0001085945],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9954737,0.0001576183,0.002474414,0.0004622157,0.0002554025,0.0002147481,0.000007694934,0.000009960875,0.0009442114],"genre_scores_gemma":[0.998351,0.00007585953,0.00003110874,0.0001366662,0.0003188929,0.0000367126,0.0002261049,0.00001274602,0.000810904],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007905927,"threshold_uncertainty_score":0.3432263,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0098776555937281,"score_gpt":0.2005460525987634,"score_spread":0.1906683970050353,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}