{"id":"W1972729597","doi":"10.4161/onci.19534","title":"Combined vaccination and immunostimulatory antibodies provides durable cure of murine melanoma and induces transcriptional changes associated with positive outcome in human melanoma patients","year":2012,"lang":"en","type":"article","venue":"OncoImmunology","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"Canadian Institutes of Health Research; Terry Fox Foundation; McMaster University","keywords":"Melanoma; Immune system; Vaccination; Medicine; Immunotherapy; Tumor microenvironment; Immunology; Antibody; Cancer research; Cytokine; Immunity","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000197904,0.0002693548,0.000362243,0.0001784555,0.0001094758,0.0002487017,0.00009603288,0.0001915938,0.0007285008],"category_scores_gemma":[0.0001000121,0.00008548448,0.0001754444,0.00008834765,0.0001424913,0.00009122123,0.0001293414,0.0004323515,0.0001963893],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001620874,"about_ca_system_score_gemma":0.0001149708,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002549746,"about_ca_topic_score_gemma":0.0003729188,"domain_scores_codex":[0.9999008,0.00001927045,0.000006399678,0.00002288628,0.00001808125,0.0000324124],"domain_scores_gemma":[0.9999455,0.000008906492,0.00001241995,0.00001013582,0.000004260515,0.00001873135],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001093682,0.0007009049,0.003812348,0.00004190719,0.00003053786,0.0001625796,0.00003980686,0.0002560022,0.9796154,0.00007539678,0.0001696295,0.01400178],"study_design_scores_gemma":[0.0006247098,0.03558646,0.08405014,0.00002498744,0.000236719,0.003390153,0.00009808592,0.0042629,0.862851,0.0001619994,0.008692816,0.00002013659],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9980237,0.0006014345,0.0005965026,0.00003401087,0.0000107604,0.00004046757,0.00006206722,0.00003564816,0.0005955138],"genre_scores_gemma":[0.9986385,0.0002118091,0.0003513707,0.00002747563,0.000007950073,0.0000262504,0.0001638016,0.000004555432,0.0005683125],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007285008,"threshold_uncertainty_score":0.002437055,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0140100056271887,"score_gpt":0.2495361660043427,"score_spread":0.235526160377154,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}