{"id":"W1972737284","doi":"10.1016/j.diff.2010.05.007","title":"Cellular reprogramming of human amniotic fluid cells to express insulin","year":2010,"lang":"en","type":"article","venue":"Differentiation","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"Michael Smith Health Research BC","keywords":"Reprogramming; Biology; Cell biology; Insulin; Reporter gene; Transplantation; Progenitor cell; Gene expression; Cell; Transcription factor; Stem cell; Cell culture; Internal medicine; Endocrinology; Gene; Genetics; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002718105,0.0002570883,0.000234776,0.0002819002,0.0001959658,0.0005868375,0.0001644407,0.0002430017,0.001476555],"category_scores_gemma":[0.0002311787,0.0001140081,0.0003302667,0.0001962126,0.0001958926,0.000169465,0.0003515996,0.0004085995,0.0004523057],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002153425,"about_ca_system_score_gemma":0.0001762746,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004797056,"about_ca_topic_score_gemma":0.0004600359,"domain_scores_codex":[0.9998125,0.00004149167,0.00002503742,0.00003558887,0.0000490979,0.00003621243],"domain_scores_gemma":[0.9999193,0.0000229203,0.00001182557,0.00002499872,0.00001165735,0.000009294835],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001471898,0.00002491351,0.0003913856,0.00003775774,0.0000118197,0.0002340691,0.0001405841,0.0001433249,0.9917226,0.0004877929,0.00007985854,0.006578664],"study_design_scores_gemma":[0.00001917217,0.0001317965,0.002177925,0.00001093446,0.00003863854,0.0003926365,0.0001059518,0.0005894402,0.9825552,0.0001598441,0.01381212,0.000006341658],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9751892,0.002553809,0.008010482,0.000190481,0.0003251545,0.0001172007,0.0006330659,0.00009447161,0.01288615],"genre_scores_gemma":[0.9911686,0.0009805384,0.002231543,0.00007588883,0.00002001094,0.00003420177,0.0003506627,0.00002290372,0.005115682],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001476555,"threshold_uncertainty_score":0.004939556,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01295325442786101,"score_gpt":0.2521311915030603,"score_spread":0.2391779370751993,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}