{"id":"W1972737284","doi":"10.1016/j.diff.2010.05.007","title":"Cellular reprogramming of human amniotic fluid cells to express insulin","year":2010,"lang":"en","type":"article","venue":"Differentiation","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"Michael Smith Health Research BC","keywords":"Reprogramming; Biology; Cell biology; Insulin; Reporter gene; Transplantation; Progenitor cell; Gene expression; Cell; Transcription factor; Stem cell; Cell culture; Internal medicine; Endocrinology; Gene; Genetics; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001021363,0.00008902546,0.0001983283,0.000119305,0.00004405555,0.00001444575,0.00004775543,0.00007387772,0.0004488215],"category_scores_gemma":[0.0001168122,0.00007935829,0.00006479076,0.0001241355,0.00002116537,0.00003757017,0.00002177487,0.0001048035,0.00005406949],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001227383,"about_ca_system_score_gemma":0.00001254787,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002921965,"about_ca_topic_score_gemma":0.00000263883,"domain_scores_codex":[0.9992453,0.00001887971,0.0002377511,0.0001800493,0.0001857892,0.00013227],"domain_scores_gemma":[0.9993752,0.00003088954,0.00007921795,0.0003101283,0.00009382285,0.00011069],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002395976,0.000159665,0.02342961,0.00007041503,0.00001880535,7.88392e-7,0.000269446,0.000001391063,0.9730934,0.0002913005,0.0002061484,0.00243507],"study_design_scores_gemma":[0.0006603538,0.0001449323,0.09844358,0.00004310661,0.00006713122,3.736788e-7,0.00005652478,0.0002898452,0.899573,0.00006729651,0.0005828408,0.00007105985],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9965466,0.00002193563,0.001759074,0.00006192106,0.0003941773,0.0002704766,0.000003501179,0.00005795895,0.000884345],"genre_scores_gemma":[0.9979452,0.000001764267,0.001186256,0.00008014685,0.0001404905,0.00001634409,0.00009645055,0.00001331018,0.0005200717],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07501397,"threshold_uncertainty_score":0.4914281,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01295325442786101,"score_gpt":0.2521311915030603,"score_spread":0.2391779370751993,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}