{"id":"W1972748461","doi":"10.1074/jbc.m112.399428","title":"Phosphatidylserine Decarboxylase 1 (Psd1) Promotes Mitochondrial Fusion by Regulating the Biophysical Properties of the Mitochondrial Membrane and Alternative Topogenesis of Mitochondrial Genome Maintenance Protein 1 (Mgm1)","year":2012,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":101,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"mitochondrial fusion; Cardiolipin; Mitochondrial fission; Phosphatidylethanolamine; Cell biology; Mitochondrion; Biology; DNAJA3; ATP–ADP translocase; Translocase of the inner membrane; Mitochondrial carrier; Inner mitochondrial membrane; Mitochondrial apoptosis-induced channel; MFN2; Mitochondrial membrane transport protein; Mitochondrial biogenesis; Biochemistry; Mitochondrial DNA; Bacterial outer membrane; Phosphatidylcholine; Phospholipid","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000978969,0.0003819271,0.0002031014,0.000193429,0.0001782048,0.0003446166,0.0001898959,0.0002516521,0.0007444573],"category_scores_gemma":[0.0001331901,0.0001092184,0.0002693897,0.0001549395,0.0002433788,0.0002399967,0.0003968271,0.0005064739,0.0002573353],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004371362,"about_ca_system_score_gemma":0.0001941222,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004090499,"about_ca_topic_score_gemma":0.0004758665,"domain_scores_codex":[0.9998806,0.00001154217,0.00001389987,0.00003472441,0.00003960617,0.00001970094],"domain_scores_gemma":[0.9998703,0.00001351821,0.00005323636,0.0000117502,0.00001706831,0.00003408902],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004764237,0.00001311493,0.0003271162,0.00002877822,0.00000289774,0.00003827595,0.000007039989,0.00004605027,0.9983916,0.00008142752,0.00002517138,0.0009909474],"study_design_scores_gemma":[0.000008718572,0.00005956824,0.007000033,0.000003803932,0.000007226653,0.0001387655,0.00002485907,0.0009583997,0.9903875,0.00006012791,0.001347842,0.000003179887],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9911514,0.001988276,0.005217787,0.0001527243,0.00003892042,0.00001632187,0.0004157081,0.0001224786,0.0008964242],"genre_scores_gemma":[0.9965238,0.0006448383,0.001276563,0.00002609672,0.000004740832,0.00001076615,0.0003959388,0.00001563032,0.001101561],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007444573,"threshold_uncertainty_score":0.003171682,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01524826009975093,"score_gpt":0.2197973428143896,"score_spread":0.2045490827146386,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}