{"id":"W1972748461","doi":"10.1074/jbc.m112.399428","title":"Phosphatidylserine Decarboxylase 1 (Psd1) Promotes Mitochondrial Fusion by Regulating the Biophysical Properties of the Mitochondrial Membrane and Alternative Topogenesis of Mitochondrial Genome Maintenance Protein 1 (Mgm1)","year":2012,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":101,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"mitochondrial fusion; Cardiolipin; Mitochondrial fission; Phosphatidylethanolamine; Cell biology; Mitochondrion; Biology; DNAJA3; ATP–ADP translocase; Translocase of the inner membrane; Mitochondrial carrier; Inner mitochondrial membrane; Mitochondrial apoptosis-induced channel; MFN2; Mitochondrial membrane transport protein; Mitochondrial biogenesis; Biochemistry; Mitochondrial DNA; Bacterial outer membrane; Phosphatidylcholine; Phospholipid","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002648324,0.0003010838,0.0005203758,0.00002172073,0.0001310741,0.00001787972,0.0005071551,0.0003566924,0.00006838559],"category_scores_gemma":[0.001001368,0.0001534051,0.0003425923,0.0001461049,0.0006867605,0.00001945162,0.0003076919,0.0003234888,6.841028e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002555697,"about_ca_system_score_gemma":0.00009024989,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001637372,"about_ca_topic_score_gemma":0.000001560354,"domain_scores_codex":[0.9978769,0.000273212,0.0008496456,0.0003145411,0.0003281549,0.0003575921],"domain_scores_gemma":[0.9980617,0.00006629592,0.001031055,0.0003816147,0.0003075036,0.0001518073],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002061448,0.0002234342,0.0004144295,0.00007745204,0.0001019881,0.000001446868,0.0001208468,0.00001319798,0.9965135,0.00001564886,0.0002294477,0.0002271962],"study_design_scores_gemma":[0.001450672,0.0005105453,0.0002990968,0.0001033547,0.00005758648,0.0001237828,0.0001230595,0.00001559914,0.9944543,0.00005295388,0.002621802,0.0001872975],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9963765,0.001436305,0.0003365955,0.0003169969,0.00089457,0.0004959923,0.00005538807,0.000005159473,0.000082551],"genre_scores_gemma":[0.9942145,0.0001437297,0.002170755,0.00006475251,0.002897537,0.00002823659,0.00001739451,0.00002087642,0.0004422202],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002392354,"threshold_uncertainty_score":0.6255679,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01524826009975093,"score_gpt":0.2197973428143896,"score_spread":0.2045490827146386,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}