{"id":"W1972785878","doi":"10.2217/fon.10.145","title":"Novel Targeted Agents on the Horizon for Castration-Resistant Prostate Cancer","year":2010,"lang":"en","type":"review","venue":"Future Oncology","topic":"Prostate Cancer Treatment and Research","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"Vancouver General Hospital","funders":"","keywords":"Prostate cancer; Medicine; Androgen receptor; Androgen deprivation therapy; Cancer research; Testosterone (patch); Orchiectomy; Androgen; Prostate; Cancer; Oncology; Internal medicine; Bioinformatics; Hormone; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003910071,0.0004175493,0.001281136,0.0001430728,0.0002281187,0.00002749404,0.0002228535,0.0007683067,0.0003799457],"category_scores_gemma":[0.00008238874,0.0002041365,0.0004142271,0.0002574198,0.0001335022,0.00002452358,0.00004058696,0.001127988,0.00005219829],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007556236,"about_ca_system_score_gemma":0.003041571,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004352761,"about_ca_topic_score_gemma":0.0003073764,"domain_scores_codex":[0.9981593,0.0001022183,0.0004288356,0.0005071103,0.0002876793,0.0005148206],"domain_scores_gemma":[0.9984998,0.0003548759,0.0003103962,0.0004495296,0.0002166079,0.00016878],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0007287523,0.0003023234,0.000002085497,0.004336745,0.0004823449,0.00006505571,0.0001149695,9.621629e-8,0.0001780613,0.0007568555,0.04206216,0.9509705],"study_design_scores_gemma":[0.001750416,0.002228437,0.00002451985,0.001942849,0.0009660062,0.00004058908,0.00005452315,0.000002060213,0.00003415618,0.00002181732,0.9927471,0.0001874839],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00004260023,0.9809052,0.00000404286,0.006750881,0.002514531,0.006299425,0.001038665,0.00003994384,0.002404714],"genre_scores_gemma":[0.00001102581,0.9804717,0.0003014391,0.0003473788,0.003557322,0.004534102,0.00125286,0.00008280664,0.009441308],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9507831,"threshold_uncertainty_score":0.8324446,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09929114834197945,"score_gpt":0.4364736487192613,"score_spread":0.3371825003772818,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}