{"id":"W1972878197","doi":"10.1152/ajplung.00170.2012","title":"NOX2 (gp91<sup>phox</sup>) is a predominant O<sub>2</sub> sensor in a human airway chemoreceptor cell line: biochemical, molecular, and electrophysiological evidence","year":2012,"lang":"en","type":"article","venue":"American Journal of Physiology-Lung Cellular and Molecular Physiology","topic":"Neuroscience of respiration and sleep","field":"Neuroscience","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"NADPH oxidase; Western blot; Ion channel; Biophysics; Chemistry; NOX4; Biology; Cell biology; Molecular biology; Biochemistry; Reactive oxygen species; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001327405,0.0003464527,0.0003132328,0.0001318184,0.0001784043,0.0003952618,0.0002695663,0.0004161183,0.0006924724],"category_scores_gemma":[0.000134888,0.0001803828,0.0003090058,0.0002252253,0.000207165,0.000370253,0.0002741741,0.0003849524,0.0005298248],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001630348,"about_ca_system_score_gemma":0.000106368,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000555786,"about_ca_topic_score_gemma":0.0004354043,"domain_scores_codex":[0.9998035,0.00001946851,0.0000183915,0.00006441059,0.00006734496,0.00002693666],"domain_scores_gemma":[0.9999217,0.000008369087,0.00002271535,0.00001236341,0.00001454779,0.00002027689],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003843926,0.00001294283,0.0006040906,0.00002228053,0.000006125434,0.0001021815,0.000009800464,0.00001172317,0.9987099,0.00003554928,0.00002307371,0.0004239211],"study_design_scores_gemma":[0.00001197316,0.0002078573,0.02842574,0.000005191238,0.00002839326,0.002607815,0.00005615319,0.001189394,0.9649233,0.0000924159,0.002444863,0.000006913124],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9846351,0.003406689,0.009721849,0.0002030399,0.00004196483,0.00003766101,0.0007685142,0.00008005559,0.001105098],"genre_scores_gemma":[0.9902982,0.001461824,0.004696309,0.00009862491,0.00002996772,0.00003906626,0.001875861,0.00001870188,0.001481484],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006924724,"threshold_uncertainty_score":0.002316594,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01060241371262245,"score_gpt":0.2517580352633613,"score_spread":0.2411556215507389,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}