{"id":"W1972907064","doi":"10.1371/journal.pone.0095600","title":"Longer Telomere Length in COPD Patients with α1-Antitrypsin Deficiency Independent of Lung Function","year":2014,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Telomeres, Telomerase, and Senescence","field":"Medicine","cited_by":30,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Paul's Hospital","funders":"Michael Smith Health Research BC","keywords":"Telomere; COPD; Senescence; Lung; Pathogenesis; Telomerase; Medicine; Internal medicine; Pulmonary function testing; Oxidative stress; Immunology; Pathology; Gastroenterology; Biology; DNA; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003169632,0.0002665101,0.0004584472,0.001068916,0.0004316583,0.0005163309,0.0001717893,0.0005844936,0.001365776],"category_scores_gemma":[0.001652258,0.0001981194,0.0002300558,0.0008846228,0.0002732148,0.0002741264,0.0002488351,0.0004194273,0.0002066966],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001819076,"about_ca_system_score_gemma":0.0001203394,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006457154,"about_ca_topic_score_gemma":0.0008029929,"domain_scores_codex":[0.9997919,0.00003825594,0.00003803368,0.00006560509,0.00003677393,0.00002935373],"domain_scores_gemma":[0.9988613,0.0002536508,0.000523249,0.00008059078,0.0001182736,0.000163023],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0008962136,0.0000357053,0.9858751,0.00003371033,0.00005146862,0.0005101633,0.0001812029,0.00004415181,0.008897375,0.0000325299,0.00007227136,0.003370072],"study_design_scores_gemma":[0.00001042351,0.0002305629,0.9965613,0.000006729485,0.00004058852,0.002047589,0.0001243758,0.0001074672,0.0006365826,0.00005814043,0.0001713299,0.000004819209],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9992285,0.0004726489,0.00007076783,0.00002081791,0.000003918649,0.000002045083,0.00006260875,0.000003533202,0.000135101],"genre_scores_gemma":[0.9995862,0.0001180533,0.00006910815,0.0000141995,0.000008227589,0.000002178465,0.00008261852,0.000001195115,0.0001183744],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001365776,"threshold_uncertainty_score":0.004568994,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01591750577377929,"score_gpt":0.2042449684461308,"score_spread":0.1883274626723515,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}