{"id":"W1972924392","doi":"10.1016/j.virol.2009.02.039","title":"Identification of a lipid kinase as a host factor involved in hepatitis C virus RNA replication","year":2009,"lang":"en","type":"article","venue":"Virology","topic":"Hepatitis C virus research","field":"Medicine","cited_by":145,"is_retracted":false,"has_abstract":false,"ca_institutions":"Boehringer Ingelheim (Canada)","funders":"Galápagos","keywords":"Biology; Gene knockdown; Small hairpin RNA; Virology; RNA interference; Replicon; Gene silencing; Viral replication; Host factor; Gene; Small interfering RNA; Oligonucleotide; Molecular biology; RNA; Virus; Genetics; Genome","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002360498,0.0003810482,0.0002832075,0.0003910314,0.0005255532,0.0005720338,0.0002551952,0.0003823506,0.001395402],"category_scores_gemma":[0.0003133699,0.0001667553,0.0003943949,0.000188968,0.0003449213,0.0005263459,0.0003293894,0.0005298202,0.0006546726],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007774167,"about_ca_system_score_gemma":0.000397685,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000787499,"about_ca_topic_score_gemma":0.0004853892,"domain_scores_codex":[0.9999143,0.00001453562,0.000007122206,0.00001741515,0.00001683907,0.0000297593],"domain_scores_gemma":[0.9998376,0.00005493589,0.00002126009,0.00002482548,0.00002442958,0.00003695319],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001301502,0.0000503774,0.001189557,0.00007653738,0.00001270519,0.0003740975,0.000033762,0.0001497622,0.9923661,0.000757585,0.0001047266,0.003583331],"study_design_scores_gemma":[0.00006400008,0.0003408369,0.01328591,0.00001086102,0.00004004469,0.001089085,0.0001023338,0.002896502,0.9776203,0.0007295609,0.003802503,0.00001792068],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9883566,0.002859116,0.005134173,0.0004105596,0.00006720096,0.0000684544,0.0005344658,0.00006151223,0.002507909],"genre_scores_gemma":[0.9917518,0.0009680888,0.003927805,0.00006525873,0.00002955287,0.0000298352,0.0008467872,0.00001199796,0.002368929],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001395402,"threshold_uncertainty_score":0.005640626,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0328058799485943,"score_gpt":0.3436462732751762,"score_spread":0.3108403933265819,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}