{"id":"W1972964227","doi":"10.1016/j.vaccine.2005.08.095","title":"Comparison of the safety and immunogenicity of hepatitis B virus surface antigen co-administered with an immunostimulatory phosphorothioate oligonucleotide and a licensed hepatitis B vaccine in healthy young adults","year":2005,"lang":"en","type":"article","venue":"Vaccine","topic":"Hepatitis B Virus Studies","field":"Medicine","cited_by":133,"is_retracted":false,"has_abstract":false,"ca_institutions":"British Columbia Children's Hospital; Dalhousie University; Izaak Walton Killam Health Centre","funders":"Clinical Trial Center, China Medical University Hospital","keywords":"Immunogenicity; Virology; Antigen; Oligonucleotide; Medicine; Hepatitis B virus; Hepatitis A vaccine; Immunology; Virus; Biology; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001529433,0.0003202049,0.0006199225,0.0003123715,0.0002594346,0.000311712,0.0001735848,0.0006126011,0.0007493975],"category_scores_gemma":[0.001601936,0.0002580497,0.0004878866,0.0002142525,0.000444273,0.0004968704,0.0001858171,0.0004934928,0.0001761816],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001960762,"about_ca_system_score_gemma":0.000356764,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008383304,"about_ca_topic_score_gemma":0.0006687262,"domain_scores_codex":[0.999445,0.0003080665,0.00004041643,0.00005500059,0.00007532976,0.00007621088],"domain_scores_gemma":[0.9990695,0.0004415101,0.0001130642,0.0000606601,0.0001277047,0.0001876341],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.4140689,0.03172083,0.162442,0.0009094584,0.0009436276,0.001120253,0.003364823,0.0004823377,0.3227469,0.0003773613,0.0002929014,0.06153057],"study_design_scores_gemma":[0.005493183,0.858195,0.1032677,0.00002297837,0.0004875377,0.0005104247,0.0004976791,0.0003285984,0.03038415,0.0000708738,0.0007259858,0.0000158787],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9997155,0.0001266454,0.00003258228,0.000006202187,0.000005839076,0.0000171784,0.000009071518,8.856387e-7,0.00008601729],"genre_scores_gemma":[0.9994525,0.0001668577,0.00004378,0.00002540994,0.00002893207,0.000017968,0.00004172142,0.000001254344,0.0002215395],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001529433,"threshold_uncertainty_score":0.008088529,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01484237908852917,"score_gpt":0.2956790418711713,"score_spread":0.2808366627826421,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}