{"id":"W1973041235","doi":"10.1021/bi400774m","title":"The Lid Domain of the MCP Hydrolase DxnB2 Contributes to the Reactivity toward Recalcitrant PCB Metabolites","year":2013,"lang":"en","type":"article","venue":"Biochemistry","topic":"Enzyme Structure and Function","field":"Materials Science","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"National Center for Research Resources; National Institute of General Medical Sciences; National Cancer Institute","keywords":"Reactivity (psychology); Hydrolase; Chemistry; Domain (mathematical analysis); Stereochemistry; Biochemistry; Computational biology; Enzyme; Biology; Medicine; Mathematics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001081725,0.0003904737,0.0002084194,0.0001074729,0.0001224862,0.0003510477,0.0002209655,0.0002870563,0.001805473],"category_scores_gemma":[0.000123518,0.0001749919,0.0002434437,0.00008150984,0.0001979374,0.0001775725,0.0003299762,0.0004160566,0.0007747968],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003791978,"about_ca_system_score_gemma":0.0001710881,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001002884,"about_ca_topic_score_gemma":0.0007856532,"domain_scores_codex":[0.9999123,0.0000127744,0.000005495505,0.00002196896,0.00001976526,0.00002767928],"domain_scores_gemma":[0.999923,0.000009763605,0.0000219242,0.000007303172,0.000008735561,0.00002934471],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001748685,0.00003231268,0.001880112,0.00003898467,0.000005855332,0.0001690816,0.00002029018,0.0001039311,0.9960395,0.0001111223,0.0001047437,0.00131926],"study_design_scores_gemma":[0.000027729,0.0001309002,0.02549406,0.000009498151,0.00001706984,0.0009371327,0.00009270437,0.002637333,0.9662685,0.00006898519,0.00430518,0.00001093456],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9969288,0.0004991136,0.001239281,0.00005903847,0.00001508777,0.000006135263,0.0002279989,0.00005335243,0.0009712956],"genre_scores_gemma":[0.9969583,0.0001143448,0.0007007035,0.00003350684,0.000003156082,0.000005585528,0.0005289353,0.0000124384,0.001643089],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001805473,"threshold_uncertainty_score":0.006039917,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006193140698768033,"score_gpt":0.2059951123578378,"score_spread":0.1998019716590698,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}