{"id":"W1973065567","doi":"10.1021/ol702982x","title":"The Use of Phosphine Ligands to Control the Regiochemistry of Pd-Catalyzed Hydrostannations of 1-Alkynes:  Synthesis of (<i>E</i>)-1-Tributylstannyl-1-alkenes","year":2008,"lang":"en","type":"article","venue":"Organic Letters","topic":"Catalytic Cross-Coupling Reactions","field":"Chemistry","cited_by":87,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Waterloo","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Regioselectivity; Chemistry; Phosphine; Palladium; Catalysis; Ligand (biochemistry); Medicinal chemistry; Combinatorial chemistry; Stereochemistry; Organic chemistry; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002620982,0.0002344728,0.0005182365,0.00005820205,0.0002189552,0.00001863572,0.0006627298,0.0001190997,0.00008762028],"category_scores_gemma":[0.002179029,0.0001698067,0.0002719333,0.0005866794,0.0008946124,0.0001008969,0.0001088797,0.0002012178,0.000003904569],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001013167,"about_ca_system_score_gemma":0.0001794767,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000250995,"about_ca_topic_score_gemma":0.00003472028,"domain_scores_codex":[0.9980211,0.000003879647,0.0008909015,0.0002807947,0.0005162451,0.0002871174],"domain_scores_gemma":[0.9953644,0.002066434,0.0007532804,0.001352951,0.0003837162,0.00007927734],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001396506,0.0001333594,0.002123521,0.0001374432,0.0002287807,0.000003455524,0.0006373433,0.0002362546,0.9928282,0.00002256309,0.003448294,0.00006109888],"study_design_scores_gemma":[0.00060309,0.00001058078,0.0008058244,0.0001263603,0.0002048391,0.00003765432,0.0003355179,0.00009613231,0.9970151,0.000009307108,0.000606048,0.0001496143],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9931201,0.0001880321,0.0001836381,0.005505684,0.00006892983,0.0001664801,0.0007110114,0.00003203114,0.00002407457],"genre_scores_gemma":[0.9993957,0.0001310901,0.00003167006,0.0001234777,0.0000578792,0.00002699602,0.00002877077,0.00004527907,0.000159154],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006275564,"threshold_uncertainty_score":0.6924518,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01608515103277283,"score_gpt":0.2190395821880309,"score_spread":0.202954431155258,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}