{"id":"W1973080999","doi":"10.6000/1929-5030.2014.03.03.5","title":"Synthesis and Characterization of N-Substituted Tetrahydroiso-quinoline Derivatives via a Pictet-Spengler Condensation","year":2014,"lang":"en","type":"article","venue":"Journal of Applied Solution Chemistry and Modeling","topic":"Synthesis and Biological Activity","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Maharaja Sayajirao University of Baroda","keywords":"Pictet–Spengler reaction; Condensation; Tetrahydroisoquinoline; Chemistry; Characterization (materials science); Organic chemistry; Materials science; Nanotechnology; Physics; Thermodynamics","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001879913,0.0002191974,0.0001981623,0.0002019917,0.0001207034,0.0001312435,0.0002616477,0.0002127788,0.001585512],"category_scores_gemma":[0.0002155477,0.00008696994,0.0001547215,0.0001837255,0.0001380587,0.0001964953,0.00009127405,0.0003009209,0.0005361451],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002159811,"about_ca_system_score_gemma":0.0001520037,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004286219,"about_ca_topic_score_gemma":0.0006273169,"domain_scores_codex":[0.9999106,0.00001589644,0.000007506083,0.0000200268,0.00003222821,0.00001384112],"domain_scores_gemma":[0.9998968,0.00001749949,0.00002680578,0.00001316647,0.00002830232,0.00001744107],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004022922,0.00001539795,0.00004721767,0.00003801181,0.000002341131,0.00005891203,0.00001817234,0.0001466742,0.9976268,0.000104427,0.00004311811,0.001858703],"study_design_scores_gemma":[0.000009400648,0.0004128357,0.0009885328,0.000003419567,0.000005655543,0.0001702474,0.000008834967,0.0004895501,0.9953778,0.0000303018,0.002496007,0.00000733237],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9683916,0.003083281,0.02112286,0.00007603928,0.00003423687,0.0002072558,0.001102048,0.0001612271,0.005821472],"genre_scores_gemma":[0.9779541,0.001679593,0.01419421,0.00005650552,0.000013182,0.00009115324,0.001048943,0.00002944106,0.004932884],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001585512,"threshold_uncertainty_score":0.005304098,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01700618985948664,"score_gpt":0.2264594317607548,"score_spread":0.2094532419012682,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}