{"id":"W1973089489","doi":"10.1128/jvi.75.18.8859-8863.2001","title":"Peptides Corresponding to the Heptad Repeat Motifs in the Transmembrane Protein (gp41) of Human Immunodeficiency Virus Type 1 Elicit Antibodies to Receptor-Activated Conformations of the Envelope Glycoprotein","year":2001,"lang":"en","type":"article","venue":"Journal of Virology","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":55,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"U.S. Food and Drug Administration; York University","keywords":"Biology; Gp41; Transmembrane protein; Glycoprotein; Heptad repeat; Virology; Human immunodeficiency virus (HIV); Antibody; Receptor; Envelope (radar); Viral envelope; Transmembrane domain; Membrane protein; Peptide sequence; Cell biology; Molecular biology; Genetics; Epitope; Gene; Membrane","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002144268,0.0003778956,0.0001235009,0.0001987498,0.0001330575,0.0002229148,0.0001078292,0.0004536566,0.0009492352],"category_scores_gemma":[0.0002295262,0.0001568516,0.0001575373,0.0001080248,0.0002043576,0.0001838908,0.0001844839,0.0004739623,0.0003963972],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001776375,"about_ca_system_score_gemma":0.00007943541,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001165249,"about_ca_topic_score_gemma":0.0002383878,"domain_scores_codex":[0.9998655,0.00002932833,0.000006149247,0.00001883458,0.00003151255,0.00004861239],"domain_scores_gemma":[0.9998631,0.00004894759,0.00003330511,0.000009898123,0.00001261724,0.00003205228],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001844373,0.0001146472,0.0004688984,0.00003987461,0.000006816455,0.0001160429,0.00002859805,0.00009637963,0.9959348,0.0001393357,0.00007326248,0.002797054],"study_design_scores_gemma":[0.0002398637,0.002021782,0.01801136,0.00002934885,0.00004897704,0.001401885,0.00009404287,0.001061388,0.9732339,0.0003702201,0.003475552,0.0000116776],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.99801,0.000406421,0.0005419752,0.00003359091,0.00001265714,0.0000212061,0.00003540154,0.00001079169,0.000928118],"genre_scores_gemma":[0.997192,0.0005280285,0.0009002179,0.0000927337,0.0000195729,0.00001410173,0.0002063585,0.00000574412,0.001041281],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009492352,"threshold_uncertainty_score":0.003175497,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02251978823055267,"score_gpt":0.2910485157915663,"score_spread":0.2685287275610136,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}