{"id":"W1973176067","doi":"10.1016/s0378-4347(01)00330-9","title":"Validation of a high-performance liquid chromatographic assay for the quantification of adenovirus type 5 particles","year":2001,"lang":"en","type":"article","venue":"Journal of Chromatography B Biomedical Sciences and Applications","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":27,"is_retracted":false,"has_abstract":false,"ca_institutions":"Biotechnology Research Institute","funders":"","keywords":"Chromatography; Detection limit; Absorbance; Lysis; Elution; High-performance liquid chromatography; Chemistry; Correlation coefficient; Reproducibility; Analytical Chemistry (journal); Calibration curve; Mathematics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001177019,0.00006647014,0.0001301363,0.0001559438,0.0001629319,0.00001659439,0.0003129526,0.0000594812,0.000008855091],"category_scores_gemma":[0.00004695697,0.00004196931,0.00008216024,0.0009723507,0.0009433697,0.00001330537,0.00002562834,0.00004827419,2.897258e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000002496585,"about_ca_system_score_gemma":0.0001085527,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001006701,"about_ca_topic_score_gemma":0.000004534277,"domain_scores_codex":[0.9989925,0.00004577042,0.0003818168,0.000128259,0.0003191324,0.0001325235],"domain_scores_gemma":[0.9990656,0.00009504756,0.0003545928,0.0001609604,0.000252644,0.00007119965],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000402055,0.0001550045,0.003133152,0.00003330281,0.00006400858,6.929878e-8,0.00002135613,0.00007610062,0.9817806,0.0004875593,0.0001350403,0.0137117],"study_design_scores_gemma":[0.0005819179,0.006151702,0.009300012,0.00004138961,0.00005698597,0.00003314534,0.00013977,0.000556374,0.9745663,0.0005811785,0.007896477,0.00009468578],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9819039,0.002073955,0.0151515,0.0005803179,0.00003547561,0.0002312426,0.00001055395,0.000002379395,0.00001069672],"genre_scores_gemma":[0.9951387,0.003966736,0.000721651,0.00002573046,0.0001026099,0.00002961303,0.000008078639,0.000004542754,0.000002318132],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01442985,"threshold_uncertainty_score":0.3475885,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02618903097981441,"score_gpt":0.3178674869674097,"score_spread":0.2916784559875953,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}