{"id":"W1973180811","doi":"10.1038/nrc2841","title":"Implications and challenges of connexin connections to cancer","year":2010,"lang":"en","type":"review","venue":"Nature reviews. Cancer","topic":"Connexins and lens biology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":303,"is_retracted":false,"has_abstract":false,"ca_institutions":"Western University; University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"Connexin; Suppressor; Gap junction; Metastasis; Biology; Cancer; Cancer research; Cell adhesion; Cell biology; Neuroscience; Intracellular; Cell; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0002622632,0.0003978428,0.001443008,0.0001111365,0.00006926159,0.000009703234,0.0003126506,0.001366251,0.0001270918],"category_scores_gemma":[0.0002254302,0.0002955708,0.0003791628,0.0002005037,0.0001061369,0.000002245617,0.0001621845,0.0007015647,0.000008343392],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003034194,"about_ca_system_score_gemma":0.0003114077,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004924263,"about_ca_topic_score_gemma":0.001799555,"domain_scores_codex":[0.9982953,0.0001510726,0.0005458855,0.0006898578,0.00006154392,0.0002563057],"domain_scores_gemma":[0.9985262,0.00006121052,0.0003982849,0.0006959653,0.0001761425,0.0001422538],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000004218765,0.00001855284,0.000006630096,0.004972989,0.000112281,1.86507e-7,0.00001213098,7.661387e-8,0.0004881623,0.001913023,0.003375948,0.9890958],"study_design_scores_gemma":[0.00008856924,0.00007308672,0.00003615857,0.00313992,0.000397103,0.00002261534,0.000004956439,5.380616e-8,0.00006133067,0.00002088841,0.995832,0.0003232639],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00002508251,0.9955629,0.00001094397,0.001360762,0.0005638554,0.001223953,0.0006057976,0.000009128667,0.0006376039],"genre_scores_gemma":[0.00006316899,0.9964686,0.0001488735,0.0004872764,0.0008380132,0.001556483,0.0001254645,0.00004669585,0.0002654309],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9924561,"threshold_uncertainty_score":0.9999496,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06507170408207949,"score_gpt":0.4091429328812676,"score_spread":0.3440712287991882,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}