{"id":"W1973401983","doi":"10.1158/1538-7445.cansusc14-ia10","title":"Abstract IA10: Li-Fraumeni syndrome: p53 and beyond","year":2014,"lang":"en","type":"article","venue":"Cancer Research","topic":"Cancer-related Molecular Pathways","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children","funders":"","keywords":"Li–Fraumeni syndrome; Cancer; Germline; Context (archaeology); Medicine; Cancer syndrome; Cancer research; Germline mutation; Genetics; Biology; Internal medicine; Mutation; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001574064,0.0008833854,0.0004076539,0.001537361,0.0003685756,0.0007792892,0.0004275418,0.00100336,0.009205777],"category_scores_gemma":[0.0004826834,0.0001630483,0.0002341811,0.0006716462,0.0006297199,0.000410534,0.0003619863,0.0007452708,0.002256797],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008724527,"about_ca_system_score_gemma":0.0004821442,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002719392,"about_ca_topic_score_gemma":0.002926274,"domain_scores_codex":[0.9999158,0.00001235908,0.000008757888,0.00002164859,0.00002286915,0.00001860982],"domain_scores_gemma":[0.9998234,0.0000352778,0.00004586224,0.000006684537,0.00003397791,0.0000548218],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001324804,0.0001752664,0.116934,0.001128117,0.00014962,0.2073406,0.0005221172,0.0007688346,0.08145901,0.01257581,0.2988109,0.2788107],"study_design_scores_gemma":[0.000150893,0.0005992206,0.1839219,0.0009129184,0.0002017029,0.4690327,0.0007279461,0.001260294,0.02366637,0.01011168,0.3093266,0.0000878159],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"empirical","genre_gemma":"other","genre_scores_codex":[0.5007936,0.2260144,0.007674569,0.03987225,0.01109007,0.0002634137,0.003032709,0.001631412,0.2096276],"genre_scores_gemma":[0.8609017,0.04511847,0.002054834,0.00329846,0.004272721,0.0000608061,0.001886267,0.00009297235,0.08231383],"genre_candidate":"other","genre_consensus":null,"teacher_disagreement_score":0.009205777,"threshold_uncertainty_score":0.03079641,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04811493997834517,"score_gpt":0.3825296962434486,"score_spread":0.3344147562651035,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}