{"id":"W1973427892","doi":"10.1155/2013/268249","title":"Constitutive Optimized Production of Streptokinase in<i>Saccharomyces cerevisiae</i>Utilizing Glyceraldehyde 3-Phosphate Dehydrogenase Promoter of<i>Pichia pastoris</i>","year":2013,"lang":"en","type":"article","venue":"BioMed Research International","topic":"Viral Infectious Diseases and Gene Expression in Insects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre","funders":"Jawaharlal Nehru Technological University Hyderabad; Council of Scientific and Industrial Research, India; World Bank Group","keywords":"Pichia pastoris; Saccharomyces cerevisiae; Yeast; Recombinant DNA; Yeast extract; Biochemistry; Pichia; Chemistry; Dehydrogenase; Molecular biology; Biology; Gene; Enzyme; Fermentation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004552859,0.0001487269,0.0001942234,0.0002935494,0.00007210483,0.00003390714,0.0003219496,0.0001166843,0.0003200729],"category_scores_gemma":[0.0004240263,0.0001304656,0.0001221225,0.0002960354,0.0003799339,0.00003201483,0.0002360527,0.000155998,0.00001539281],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005170605,"about_ca_system_score_gemma":0.0001839891,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004087724,"about_ca_topic_score_gemma":0.00001742622,"domain_scores_codex":[0.9981518,0.0001862714,0.0004415036,0.0004254718,0.0004901677,0.0003047189],"domain_scores_gemma":[0.998641,0.00003230233,0.0001797985,0.0003060397,0.0007209338,0.0001199887],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003960209,0.0004069411,0.007607245,0.00007340568,0.000125021,0.00000500228,0.00008591288,0.0001694438,0.9794689,0.0002129765,0.0097084,0.001740773],"study_design_scores_gemma":[0.0011862,0.0003115833,0.002367532,0.0001619509,0.00000699333,0.000009609783,0.0001819265,0.0002468327,0.9877312,0.0004475605,0.007192615,0.0001559821],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9957798,0.000676175,0.00009232327,0.0003948751,0.0009582334,0.0006572867,0.0000635855,0.000009870419,0.001367832],"genre_scores_gemma":[0.9976491,0.0004099854,0.0008562735,0.0000281673,0.0003135843,0.0001803223,0.0001315312,0.0000157906,0.0004151946],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008262355,"threshold_uncertainty_score":0.5320231,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02581269982171776,"score_gpt":0.3314146422859882,"score_spread":0.3056019424642705,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}