{"id":"W1973427892","doi":"10.1155/2013/268249","title":"Constitutive Optimized Production of Streptokinase in<i>Saccharomyces cerevisiae</i>Utilizing Glyceraldehyde 3-Phosphate Dehydrogenase Promoter of<i>Pichia pastoris</i>","year":2013,"lang":"en","type":"article","venue":"BioMed Research International","topic":"Viral Infectious Diseases and Gene Expression in Insects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre","funders":"Jawaharlal Nehru Technological University Hyderabad; Council of Scientific and Industrial Research, India; World Bank Group","keywords":"Pichia pastoris; Saccharomyces cerevisiae; Yeast; Recombinant DNA; Yeast extract; Biochemistry; Pichia; Chemistry; Dehydrogenase; Molecular biology; Biology; Gene; Enzyme; Fermentation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003536781,0.0004815999,0.0006076652,0.0002507054,0.0001104975,0.0005371719,0.0002799618,0.0001683714,0.0003741607],"category_scores_gemma":[0.0002527122,0.000182989,0.0003887887,0.000463994,0.0001661221,0.0001640781,0.0002450651,0.0003638449,0.0001714026],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000335251,"about_ca_system_score_gemma":0.000391193,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008047044,"about_ca_topic_score_gemma":0.001274345,"domain_scores_codex":[0.999612,0.00006941504,0.00005799385,0.00008847644,0.0001332185,0.00003885866],"domain_scores_gemma":[0.9999161,0.00001617396,0.0000320711,0.000009009444,0.00001705917,0.000009627287],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007871223,0.00002840596,0.0003128692,0.00007574296,0.000006921601,0.0000309422,0.00001138143,0.0004684873,0.996775,0.00006529107,0.00003077768,0.002115601],"study_design_scores_gemma":[0.000007966453,0.0002691966,0.002126299,0.000005875316,0.00002805805,0.00008040947,0.00002126425,0.002531408,0.9933688,0.00003724809,0.001515886,0.000007721307],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9628345,0.001311611,0.03218342,0.00007485914,0.00004971299,0.000169531,0.001232143,0.0003147179,0.001829602],"genre_scores_gemma":[0.9332744,0.001331326,0.06113241,0.00003120656,0.000008175019,0.0001749782,0.002074091,0.00007812804,0.001895326],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008047044,"threshold_uncertainty_score":0.002432406,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02581269982171776,"score_gpt":0.3314146422859882,"score_spread":0.3056019424642705,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}