{"id":"W1973448897","doi":"10.1088/1478-3975/7/2/021001","title":"Mechanisms governing the control of mRNA translation","year":2010,"lang":"en","type":"review","venue":"Physical Biology","topic":"PI3K/AKT/mTOR signaling in cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":81,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"National Cancer Institute; Canadian Institutes of Health Research; Terry Fox Foundation","keywords":"Translation (biology); Messenger RNA; Computational biology; Protein biosynthesis; Biology; Intracellular; Cell biology; Bioinformatics; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001969754,0.0002744815,0.0008069694,0.00002121059,0.00004711051,0.000006540238,0.0004389012,0.0005048289,0.00001668055],"category_scores_gemma":[0.00007466716,0.0001708168,0.0005158334,0.00007631161,0.0001998684,0.000001279249,0.00005468236,0.000406326,0.00002458709],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001223654,"about_ca_system_score_gemma":0.0001361332,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000087027,"about_ca_topic_score_gemma":0.000004628218,"domain_scores_codex":[0.9987478,0.000235801,0.0003116622,0.0003864683,0.00008669063,0.0002315571],"domain_scores_gemma":[0.9989324,0.0001809777,0.0003529789,0.0004418025,0.00005162052,0.00004023079],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00002001151,0.00004349294,9.919377e-7,0.0004357115,0.000206441,3.120248e-7,0.00001262941,0.000002143315,0.2023685,0.002612532,0.00009262,0.7942046],"study_design_scores_gemma":[0.0002063219,0.0002646747,7.151775e-7,0.0001805907,0.0003245527,0.000005490555,0.000001403031,0.00002842509,0.003985881,0.0009149649,0.9938914,0.0001955466],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001223902,0.9870564,0.01126347,0.00004069887,0.0003370112,0.0004080006,0.0003023262,0.00001223623,0.0004575143],"genre_scores_gemma":[0.03522176,0.9624927,0.0002699533,0.0001115177,0.001152488,0.0001372128,0.0004949358,0.00005454462,0.00006486641],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9937988,"threshold_uncertainty_score":0.6965708,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02812400312123418,"score_gpt":0.3321351091403312,"score_spread":0.304011106019097,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}