{"id":"W1973542661","doi":"10.1016/j.virol.2010.08.013","title":"Formation of immature and mature genomic RNA dimers in wild-type and protease-inactive HIV-1: Differential roles of the Gag polyprotein, nucleocapsid proteins NCp15, NCp9, NCp7, and the dimerization initiation site","year":2010,"lang":"en","type":"article","venue":"Virology","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":37,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University; Jewish General Hospital","funders":"Canadian Institutes of Health Research","keywords":"Zinc finger; Linker; Biology; Protease; RNA; Mutant; Human immunodeficiency virus (HIV); Cell biology; Virology; Molecular biology; Genetics; Biochemistry; Enzyme; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001672303,0.0001356269,0.0002531811,0.0001025036,0.0001456601,0.000009807722,0.00008780038,0.0002829094,0.0000293815],"category_scores_gemma":[0.00009916003,0.00007872614,0.00002844017,0.0001175056,0.000723781,0.000113142,0.0001150476,0.0004418886,0.000005330639],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001174522,"about_ca_system_score_gemma":0.00003769792,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000147891,"about_ca_topic_score_gemma":0.0003504595,"domain_scores_codex":[0.9989682,0.0003957123,0.0002241135,0.0001821891,0.00004221615,0.0001875529],"domain_scores_gemma":[0.9994354,0.00009286236,0.0002153119,0.0001813984,0.00005651984,0.00001854188],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00232395,0.00007348679,0.00508488,0.00005145012,0.00007089896,0.00000106007,0.002634821,0.000001666356,0.9865942,0.0008141653,0.00001568437,0.002333763],"study_design_scores_gemma":[0.006285036,0.0005083881,0.688449,0.00004727761,0.0001042167,0.0001081675,0.0004120704,0.0001822281,0.3026024,0.0009499297,0.0002097618,0.0001414739],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.996159,0.001027868,0.00005984121,0.001153921,0.00007894055,0.001373933,0.00009058148,0.000007924474,0.00004795599],"genre_scores_gemma":[0.9994969,0.0001781677,0.00003847136,0.00003520444,0.00001429001,0.00007758127,0.0001185179,0.000009491899,0.00003136291],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6839917,"threshold_uncertainty_score":0.3210359,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003836944664234506,"score_gpt":0.2022963732414007,"score_spread":0.1984594285771662,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}