{"id":"W1973542661","doi":"10.1016/j.virol.2010.08.013","title":"Formation of immature and mature genomic RNA dimers in wild-type and protease-inactive HIV-1: Differential roles of the Gag polyprotein, nucleocapsid proteins NCp15, NCp9, NCp7, and the dimerization initiation site","year":2010,"lang":"en","type":"article","venue":"Virology","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":37,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University; Jewish General Hospital","funders":"Canadian Institutes of Health Research","keywords":"Zinc finger; Linker; Biology; Protease; RNA; Mutant; Human immunodeficiency virus (HIV); Cell biology; Virology; Molecular biology; Genetics; Biochemistry; Enzyme; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003669289,0.0003044182,0.0003077968,0.0003462383,0.0003829313,0.0006538109,0.0004047421,0.0004038107,0.001255962],"category_scores_gemma":[0.0005324677,0.0003541253,0.0003875881,0.0001221334,0.0003342066,0.0004280797,0.0002254002,0.001013063,0.0004243942],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004808314,"about_ca_system_score_gemma":0.0002370381,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004335009,"about_ca_topic_score_gemma":0.0004800947,"domain_scores_codex":[0.9997003,0.00004991662,0.00002160981,0.00008582972,0.00008398023,0.00005841006],"domain_scores_gemma":[0.9993935,0.0001578637,0.00009460621,0.00008490966,0.00007253212,0.0001966404],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001209999,0.00002086828,0.0002123083,0.0000111333,0.000004196778,0.00004616428,0.00003691991,0.00004979055,0.9988056,0.0002106571,0.00001914943,0.0004621815],"study_design_scores_gemma":[0.00002091698,0.0002556899,0.006107633,0.000005795926,0.00001819368,0.0005680964,0.00009362504,0.002108245,0.9897042,0.0002438965,0.0008626225,0.00001115381],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9965301,0.0006871009,0.001856903,0.00004089251,0.00002586983,0.000009495909,0.0001295616,0.00003901187,0.000681054],"genre_scores_gemma":[0.9943315,0.0002044148,0.002552085,0.0000476586,0.00001761538,0.00001894181,0.001082001,0.0000410564,0.001704628],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001255962,"threshold_uncertainty_score":0.004201591,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003836944664234506,"score_gpt":0.2022963732414007,"score_spread":0.1984594285771662,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}