{"id":"W1973548596","doi":"10.1159/000102534","title":"Endothelin-1-Induced Pulmonary Vasoreactivity Is Regulated by ET<sub>A</sub> and ET<sub>B</sub> Receptor Interactions","year":2007,"lang":"en","type":"article","venue":"Journal of Vascular Research","topic":"Nitric Oxide and Endothelin Effects","field":"Medicine","cited_by":62,"is_retracted":false,"has_abstract":true,"ca_institutions":"Montreal Heart Institute","funders":"Canadian Institutes of Health Research","keywords":"Vasoconstriction; Vasodilation; Hypoxic pulmonary vasoconstriction; Endothelin 1; Internal medicine; Endocrinology; Endothelin receptor; Agonist; Endothelium; Antagonist; Chemistry; Endothelins; Receptor; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003006723,0.0002442934,0.0003720146,0.0001278668,0.0001492138,0.0003210693,0.0001774241,0.0002476762,0.002083637],"category_scores_gemma":[0.0002154593,0.0001895719,0.0003364734,0.0001001707,0.0003690727,0.0003006969,0.0002425273,0.000652865,0.0004184198],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001938391,"about_ca_system_score_gemma":0.0001573372,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001519364,"about_ca_topic_score_gemma":0.000154016,"domain_scores_codex":[0.9997914,0.0000501582,0.00001954768,0.00004224361,0.0000509681,0.00004560045],"domain_scores_gemma":[0.9996805,0.00007437244,0.0001097901,0.00001711194,0.0000248459,0.00009341704],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003230619,0.00003865698,0.000233033,0.00003652497,0.000007421609,0.00007179451,0.000009911946,0.00002772046,0.9984874,0.0000474449,0.00002283896,0.0006942871],"study_design_scores_gemma":[0.0001319818,0.001565762,0.05855767,0.00001781699,0.000067149,0.0009079347,0.000052518,0.001910595,0.9345701,0.000160859,0.002046908,0.00001065875],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9924536,0.003106049,0.002715959,0.0001462466,0.00002249293,0.00002374103,0.0001140106,0.00005193485,0.001365993],"genre_scores_gemma":[0.9952248,0.001378133,0.001794207,0.0000855917,0.00004481347,0.00004166318,0.000162305,0.00001724502,0.001251122],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002083637,"threshold_uncertainty_score":0.006970406,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03945705508869796,"score_gpt":0.3541359091129481,"score_spread":0.3146788540242501,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}