{"id":"W1973549141","doi":"10.1007/s10456-013-9374-5","title":"Neuronal sirtuin1 mediates retinal vascular regeneration in oxygen-induced ischemic retinopathy","year":2013,"lang":"en","type":"article","venue":"Angiogenesis","topic":"Sirtuins and Resveratrol in Medicine","field":"Medicine","cited_by":36,"is_retracted":false,"has_abstract":false,"ca_institutions":"Hôpital Maisonneuve-Rosemont; Université de Montréal","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Eye Institute; National Institute on Aging","keywords":"Retinal; Hypoxia (environmental); Ischemia; Retinopathy; Angiogenesis; Retina; Sirtuin 1; Regeneration (biology); Biology; Retinopathy of prematurity; Sirtuin; Neovascularization; Vascular endothelial growth factor; Medicine; Cell biology; Neuroscience; Cancer research; Endocrinology; Internal medicine; Downregulation and upregulation; Chemistry; Biochemistry; Oxygen","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003370163,0.0003387389,0.0004544274,0.0003204415,0.000302782,0.0004515824,0.0003937398,0.0004895983,0.001783375],"category_scores_gemma":[0.0001973266,0.0001874352,0.0006012254,0.0001865672,0.0004662715,0.000443527,0.000275697,0.0009743195,0.000338593],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005841394,"about_ca_system_score_gemma":0.0003862328,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001881877,"about_ca_topic_score_gemma":0.002815841,"domain_scores_codex":[0.9998217,0.00004112419,0.0000116483,0.00003003927,0.00003282886,0.00006274111],"domain_scores_gemma":[0.9998994,0.000008517025,0.00002601467,0.00001669827,0.00001693449,0.00003243189],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003111537,0.000227858,0.0009993686,0.0002520821,0.00008897707,0.0002832563,0.00009021447,0.0001716826,0.9814436,0.001845814,0.0006717165,0.0108138],"study_design_scores_gemma":[0.0002094796,0.001270765,0.02577886,0.00003952047,0.0002433255,0.0004628506,0.0003761308,0.001951285,0.9589626,0.001023975,0.009656144,0.00002506078],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9619259,0.0218801,0.007098074,0.001243554,0.0003518652,0.00004961865,0.0002711988,0.0002551796,0.006924478],"genre_scores_gemma":[0.992704,0.003000655,0.0008701948,0.0001384638,0.00003890837,0.0000178076,0.0001597696,0.00001444591,0.003055817],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001881877,"threshold_uncertainty_score":0.005965948,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01315510777686066,"score_gpt":0.2344578482692619,"score_spread":0.2213027404924012,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}