{"id":"W1973561132","doi":"10.1111/j.1582-4934.2003.tb00228.x","title":"Attenuation of changes in G<sub>i</sub>‐proteins and adenylyl cyclase in heart failure by an ACE inhibitor, imidapril","year":2003,"lang":"en","type":"article","venue":"Journal of Cellular and Molecular Medicine","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Boniface Hospital","funders":"Heart and Stroke Foundation of Canada","keywords":"Adenylyl cyclase; Heart failure; Internal medicine; Ventricle; Pertussis toxin; Cholera toxin; Endocrinology; Cardiac function curve; Myocardial infarction; Medicine; ACE inhibitor; G protein; Receptor; Angiotensin-converting enzyme; Cardiology; Chemistry; Blood pressure","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002032166,0.0005234156,0.0005151923,0.0002941327,0.0001481109,0.0002407907,0.0002536357,0.0003622553,0.001127378],"category_scores_gemma":[0.0001906239,0.0002440857,0.0002563244,0.0001497254,0.0004215513,0.0003028752,0.0001428307,0.001038486,0.0002768201],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002508771,"about_ca_system_score_gemma":0.0002037236,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004513063,"about_ca_topic_score_gemma":0.0008301684,"domain_scores_codex":[0.9999064,0.00001713864,0.000009855458,0.00001255795,0.00001662321,0.0000373591],"domain_scores_gemma":[0.9998459,0.0000247567,0.00004225324,0.00001492598,0.00001354732,0.00005856248],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00115799,0.0001036649,0.0002384458,0.00003111681,0.000006318587,0.00006467579,0.00001757909,0.00003269487,0.9972044,0.0000473125,0.00003148916,0.001064299],"study_design_scores_gemma":[0.0002451268,0.004420237,0.0241053,0.00001427667,0.00005476685,0.0002723825,0.00007468028,0.001059016,0.9684545,0.0001007899,0.001190457,0.000008494853],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9971514,0.001168253,0.0005160122,0.0001527204,0.00003139471,0.00002027434,0.0001395542,0.00005850021,0.000761913],"genre_scores_gemma":[0.9945657,0.001371317,0.00154339,0.000144243,0.0000476953,0.00007080142,0.0003490922,0.00002125952,0.001886562],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001127378,"threshold_uncertainty_score":0.003771484,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005580353984095528,"score_gpt":0.2185455157535848,"score_spread":0.2129651617694893,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}